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Showing result 1 - 5 of 59 swedish dissertations matching the above criteria.
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1. Zinc in cerebrospinal fluid and serum in some neurological diseases
Abstract : The trace elements zinc and copper are essential components of many enzymes, some of which are of importance for the development and function of the central nervous system. Deficiency of the metals has been shown to lead to malformations and to the loss of myelin in animals. READ MORE
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2. Gluten challenge in children with coeliac disease. With special reference to dose dependence and impact on growth markers and growth hormone secretion
Abstract : Coeliac disease is a prevalent food intolerance in both children and adults, in which ingestion of gluten causes inflammation of the small intestine. This inflammation resolves upon gluten withdrawal, and gluten challenge induces relapse of enteropathy in susceptible individuals. READ MORE
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3. Protein adducts in plasma as biomarkers of exposure to and risk of organic acid anhydrides
Abstract : Organic acid anhydrides (OAAs) are important industrial chemicals but also potent inducers of airways diseases. Many exposed workers develop specific IgE and IgG antibodies. Hexahydrophthalic anhydride (HHPA) and methylhexahydrophthalic anhydride (MHHPA) are two particularly sensitising OAAs. READ MORE
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4. Severe cerebral emergency : aspects of treatment and outcome in the intensive care patient
Abstract : Severe Traumatic Brain Injury (TBI) and aneurysmal Subarachnoid Hemorrhage (SAH) are severe cerebral emergencies. They are common reasons for extensive morbidity and mortality in young people and adults in the western world. READ MORE
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5. Biomarkers of internal exposure/dose : Methods to quantify adducts to protein and DNA by LC/MS studied with benzo[a]pyrene and isocyanates
Abstract : This thesis focuses on methods for quantification by liquid chromatography/mass spectrometry (LC/MS) of specific biomarkers for internal dose of chemicals which induce toxicity through their electrophilic reactivity. In vivo such compounds are short-lived, and could feasibly be measured as their reaction products (adducts) with biomacromolecules. READ MORE