Search for dissertations about: "shotgun sequencing"
Showing result 1 - 5 of 24 swedish dissertations containing the words shotgun sequencing.
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1. Software Tools and Algorithms for Shotgun Sequence Assembly
Abstract : During the last ten years, a genomics revolution has changed the ways biological research is carried out. The draft sequence of the human genome is available, as well as the sequence of 84 other completed genomes. READ MORE
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2. Solving repeat problems in shotgun sequencing
Abstract : Shotgun sequencing is the most powerful strategy for large scale sequencing. Two main approaches exist: clone-by-clone and whole genome shotgun (WGS). In the clone-by-clone strategy, overlapping clones are amplified and then sheared in a random fashion. READ MORE
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3. Computational methods for analysis of fragmented sequence data
Abstract : Recent developments in genomic and proteomic sequencing technologies have revolutionized research in life sciences, providing new opportunities for the study of biological systems. However, modern sequence data sets are large, diverse, and heavily fragmented, which presents new challenges for their analysis and interpretation. READ MORE
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4. Thermodynamics of Protein Folding and Design
Abstract : The protein folding and protein design problems are addressed, using coarse-grained models with only two types of amino acids, hydrophobic and hydrophilic. In addition to hydrophobicity forces, the models contain sequence-independent local interactions which are found to strongly influence the thermodynamics of these models. READ MORE
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5. Microbial biofilm communities associated with degradation of sprayed concrete in subsea tunnels
Abstract : Deterioration of concrete leads to reduced structural strength implying high societal challenge with huge economic impact. In the Oslofjord subsea tunnel, complex microbial biofilm activity together with abiotic attack from saline groundwater are responsible for concrete matrix degradation and steel fiber corrosion. READ MORE