Search for dissertations about: "shuttle"

Showing result 11 - 15 of 59 swedish dissertations containing the word shuttle.

  2. 11. To degrade or not to degrade : protein handling by the proteasome

    Author : Christian Heinen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The proteasome, a large multi-subunit protease that degrades proteins, must be able to distinguish between substrates deemed for destruction and accessory proteins that should be spared. The shuttle factor Rad23 operates in close proximity to the proteasome in order to deliver proteins for their degradation. READ MORE

  4. 12. Electromechanical Phenomena in Superconducting and Normal Nanostructures

    Author : Milton Eduardo Peña-Aza; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Nanoelectromechanical systems; nanoelectromechanical Josephson junctions; metallic carbon nanotubes; ground-state cooling; chaos;

    Abstract : This thesis summarizes a series of theoretical studies on the electromechanical properties of nanostructures made of superconducting and/or metallic elements. The first part of the work is devoted to the analysis of the interactions between the electronic and mechanical degrees of freedom in suspended nanowires. READ MORE

  5. 13. Functional studies of plant hexokinases and development of genetic methods in the moss Physcomitrella patens

    Author : Mikael Ulfstedt; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Abstract : In the field of biology, model systems are frequently used for practical reasons. Model organisms possess several features that make them easy to work with in a laboratory setting. In addition they usually have a host of established genetic tools that have been developed by the research community. READ MORE

  6. 14. The bioenergetic roles of PGC-1α1, kynurenines, and GPR35 in exercise and obesity

    Author : Shamim Dadvar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Obesity is a major cause of medical comorbidity with detrimental effects on health span. Fundamentally, obesity is a condition of disrupted energy metabolism, where energy intake chronically exceeds expenditure. Over time, this disruption causes a systemic low-grade inflammation and impairs energy homeostasis. READ MORE

  7. 15. Development of new affinity proteins for neurodegenerative disorders

    Author : Linnea C. Hjelm; John Löfblom; Stefan Ståhl; Hanna Lindberg; Ylva Ivarsson; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein engineering; sequestrins; amyloid beta; alpha-synuclein; phage display; affibodies; blood–brain barrier; Transferrin receptor; receptor-mediated transcytosis; recombinant spider silk; Biotechnology; Bioteknologi;

    Abstract : Neurodegenerative disorders include a full spectrum of diagnoses, including dementias and other neuronal diseases, characterised by degradation of neurons in the brain occurring along with disease progression. Amongst the dementias, the most prevalent are Alzheimer’s (AD) and Parkinson’s disease (PD) that affect millions of people worldwide. READ MORE