Search for dissertations about: "signaling mechanisms"
Showing result 1 - 5 of 918 swedish dissertations containing the words signaling mechanisms.
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1. Melanophore signaling : regulation and application
Abstract : Melanophores are pigment-containing cells responsible for quick physiological color changes in lower vertebrates due to redistribution of melanosomes, pigment granules. We have studied melanophores from African clawed frog, Xenopus laevis. READ MORE
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2. Mechanisms of modulation of PDGFRβ signaling
Abstract : Platelet-derived growth factors (PDGF) constitute a family of five functional dimers that bind to two structurally related tyrosine kinase receptors i.e. PDGF receptor α and β (PDGFRα and PDGFRβ, respectively), controlling cell growth, proliferation, and migration in cells of mesenchymal origin. READ MORE
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3. Studies of PDGF receptor signaling in vitro and in vivo
Abstract : Platelet-derived growth factor receptor (PDGFR) signaling is essential for proliferation, migration and survival of cells of mesenchymal origin; however, its deregulation has been associated with various diseases, including cancer. The aim of this thesis was to clarify the molecular mechanisms of PDGFR signaling regulation. READ MORE
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4. Regulatory mechanisms of amino acid-induced signaling in Saccharomyces cerevisiae
Abstract : This thesis describes studies aimed at elucidating the molecular mechanisms that regulate the SPS (Ssy1-Ptr3-Ssy5) signal transduction pathway in the yeast Saccharomyces cerevisiae. This pathway is induced by extracellular amino acids and facilitates their uptake. READ MORE
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5. Chemoattractant receptor signaling and neutrophil acctivation. Involvement of the cytoskeleton
Abstract : Neutrophil granulocytes play a vital role in the host surveillance system and form the first line of defense against microbial infections. The migration of neutrophils to an infected/inflamed tissue is guided by chemoattractants released either from intruding microbes or from activated/damaged host cells. READ MORE