Search for dissertations about: "single nucleotide polymorphisms"

Showing result 11 - 15 of 220 swedish dissertations containing the words single nucleotide polymorphisms.

2. 11. Understanding the adaptive capacity of the bumblebee Bombus terrestris across native and novel environments

   Author : Cecilia Hjort; Biodiversitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bumblebees; Bombus terrestris; Pollination; Introgression; Single nucleotide polymorphisms; Whole Genome Sequencing; Landscape simplification; Gene flow; Morphology; Environmental variation; Invasion; Local adaptation; Island;

   Abstract : Anthropogenic stressors such as agricultural intensification, climate change, andincreased densities of non-native managed bees used for crop pollination arecontributing to bee declines. Understanding how and why bees have responded topast environmental changes is crucial for predicting future ones and enablingmitigation to maintain the functioning of both natural and agricultural ecosystems. READ MORE

4. 12. Autoantibodies and genetic variation in rheumatoid arthritis : aspects on susceptibility and disease course

   Author : Alf Kastbom; Thomas Skogh; Peter Söderkvist; Alex Karlsson-Parra; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; autoantibodies; single-nucleotide polymorphisms; disease course; Rheumatology; Reumatologi;

   Abstract : Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and subsequent destruction of synovial joints. Although its causes remain largely unknown, a substantial genetic contribution is known to exist. READ MORE

5. 13. Genetics of Parkinson's disease - with focus on genes of relevance for inflammation and dopamine neruon development

   Author : Anna Zettergren; Göteborgs universitet; []
   Keywords : Parkinson s disease; genetics; inflammation; single nucleotide polymorphism; dopamine neuron development; estrogen; gene; age of onset; Pitx3; estrogen receptor beta; interleukin 6;

   Abstract : Abstract GENETICS OF PARKINSON’S DISEASE - WITH FOCUS ON GENES OF RELEVANCE FOR INFLAMMATION AND DOPAMINE NEURON DEVELOPMENT Introduction: The risk to be affected by Parkinson’s disease (PD) is considered to be influenced by genetic factors. In some rare cases of familial PD, mutations in some specific genes are known to cause the disease, but in the more common sporadic form of PD the causes are probably environmental factors interacting with genetic vulnerability. READ MORE

6. 14. Reproductive Factors and Breast Cancer - Parity, Breastfeeding and Genetic Predisposition in Relation to Risk and Prognosis

   Author : Salma Butt; Kirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; subgroups; stage; survival; Breast cancer risk; parity; nulliparity; multiparity; breastfeeding; age at first birth; single nucleotide polymophisms;

   Abstract : The aim of this thesis was to study reproductive factors and genetic polymorphisms in relation to breast cancer risk and survival. An important component of this was to investigate the risk of specific breast cancer subgroups. READ MORE

7. 15. Development and Application of Genomic Resources in Non-model Bird Species

   Author : Biao Wang; Jacob Höglund; Christopher Wheat; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; genome; transcriptome; next generation sequencing; non-model species; bioinformatics; reference guided assembly; RNA-Seq; comparative genomics; gene expression; major histocompatibility complex; single nucleotide polymorphism; microsatellite; Biologi; Biology;

   Abstract : Understanding the genetic basis of biological processes is a fundamental component of modern ecology and evolutionary biology studies. With the recent advent of next generation sequencing (NGS) technologies, it is now possible to perform large genome and transcriptome projects for ecologically important non-model species. READ MORE