Search for dissertations about: "single particle analysis"

Showing result 1 - 5 of 130 swedish dissertations containing the words single particle analysis.

  2. 1. Single Molecule Detection : Microfluidic Automation and Digital Quantification

    Author : Malte Kühnemund; Mats Nilsson; Ulf Landegren; Sten Linnarsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; single molecule; digital; rolling circle amplification; magnetic particle; padlock probe; microfluidics; resistive pulse sensing; lab on chip; mobile phone microscopy; enrichment; sequencing;

    Abstract : Much of recent progress in medical research and diagnostics has been enabled through the advances in molecular analysis technologies, which now permit the detection and analysis of single molecules with high sensitivity and specificity. Assay sensitivity is fundamentally limited by the efficiency of the detection method used for read-out. READ MORE

  4. 2. Statistical methods in single particle fluorescence microscopy

    Author : Magnus Röding; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; absolute number concentration; Brownian motion; diffusion; fluorescence microscopy; image analysis; image processing; nanoparticle characterization; particle tracking; Smoluchowski process; nanoparticle characterization;

    Abstract : The aim of this thesis is stochastic modeling and statistical inference in single particle fluorescence microscopy related to the experimental observation of randomly moving particles. A central theme is the use of single particle microscopy for estimation of absolute concentration of nanoparticles performing Brownian motion. READ MORE

  5. 3. Concentration measurements in single particle microscopy

    Author : Magnus Röding; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; diffusion; fluorescence microscopy; nanoparticle characterization; number concentration; optical wide-field microscopy; single particle tracking; Smoluchowski process; diffusion;

    Abstract : The topic of this thesis is the introduction of two novel methods for using single particle microscopy as a tool for absolute number concentration measurements of Brownian particles. The key idea of both methods is that in order to estimate number concentration, the size of the (three-dimensional) particle detection region has to be estimated. READ MORE

  6. 4. Raster Image Analysis of Diffusion via Single Particle Methods

    Author : Marco Longfils; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; diffusion; single particle tracking; raster scan; confocal laser scanning microscopy; image correlation spectroscopy; raster scan;

    Abstract : Soft biomaterials are widely used in many application areas, spanning from packaging materials to pharmaceuticals. To enhance their functionalities, understanding the interplay between microstructure and mass transport properties in these materials is fundamental. READ MORE

  7. 5. Transition in Particle-laden Flows

    Author : Joy Klinkenberg; Luca Brandt; Shuisheng He; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Transition; modal analysis; non-modal analysis; multi-phase flow; particle-laden; heavy particles; light particles;

    Abstract : This thesis presents the study of laminar to turbulent transition of particle laden flows. When a flow becomes turbulent, the drag increases one order of magnitude compared to a laminar flow, therefore, much research is devoted to understand and influence the transition. READ MORE