Search for dissertations about: "single-cell"

Showing result 1 - 5 of 312 swedish dissertations containing the word single-cell.

  1. 1. Technologies for Single Cell Genome Analysis

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Erik Borgström; Afshin Ahmadian; Sten Linnarsson; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA; sequencing; single molecule; single cell; whole genome amplification; exome sequencing; emulsions; barcoding; phasin; Biotechnology; Bioteknologi;

    Abstract : During the last decade high throughput DNA sequencing of single cells has evolved from an idea to one of the most high profile fields of research. Much of this development has been possible due to the dramatic reduction in costs for massively parallel sequencing. READ MORE

  2. 2. Spatially resolved and single cell transcriptomics

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Fredrik Salmén; Joakim Lundeberg; Patrik Ståhl; Elaine R. Mardis; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; spatial; transcriptomics; single cell; 3D; RNA-sequencing; Biotechnology; Bioteknologi;

    Abstract : In recent years, massive parallel sequencing has revolutionized the field of biology and has provided us with a vast number of new discoveries in fields such as neurology, developmental biology and cancer research. A significant area is deciphering gene expression patterns, as well as other aspects of transcriptome information, such as the impact of splice variants and mutations on biological functions and disease development. READ MORE

  3. 3. Microwell devices for single-cell analyses

    University dissertation from Stockholm : KTH

    Author : Sara Lindström; Helene Andersson-Svahn; Mehmet Toner; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; microwell; miniaturization; microfluidics; cell culture; single-cell; clone; imaging; stem cell; cancer; low volume; high-throughput; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi;

    Abstract : Powerful tools for detailed cellular studies are emerging, increasing the knowledge ofthe ultimate target of all drugs: the living cell. Today, cells are commonly analyzed inensembles, i.e. thousands of cells per sample, yielding results on the average responseof the cells. READ MORE

  4. 4. DNA repair and genome organisation in mammalian cells : studies involving single-cell electrophoresis

    University dissertation from Stockholm : Stockholm University

    Author : Stefan Eriksson; Bert van Zeeland; [2000]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physical Biology; fysikalisk biologi;

    Abstract : The comet assay (single-cell electrophoresis) is a comparably new method for measurement of DNA strand breakage, primarily in eukaryotic cells. Its main advantage is that it works on the single-cell level, making it possible to detect heterogeneity in DNA damage induction and repair. READ MORE

  5. 5. Microtechnologies for single cell studies

    University dissertation from Stockholm : Stockholm University

    Author : Xu Shijun; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : .... READ MORE