Search for dissertations about: "single-cell"

Showing result 6 - 10 of 468 swedish dissertations containing the word single-cell.

  2. 6. Finding order in chaos : Dissecting single-cell heterogeneity in space and time

    Author : Christian Gnann; Emma Lundberg; Manuel D Leonetti; Lucas Pelkmans; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; non-genetic single-cell heterogeneity; cell cycle; metabolism; imaging-based subcellular proteomics; phosphoproteomics; icke-genetisk single-cell heterogenitet; cellcykel; metabolism; bildbaserad subcellulär proteomik; fosfoproteomik; Biotechnology; Bioteknologi;

    Abstract : The cell is the smallest unit of life and contains DNA, RNA, proteins and a variety of other macromolecules. In recent years, technological advances in the field of single cell biology have revealed a staggering amount of phenotypic heterogeneity between cells in a population, which were previously considered homogenous. READ MORE

  4. 7. Dynamic single-cell modelling of nutrient signalling in budding yeast

    Author : Sebastian Persson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; nutrient signalling; single-cell; mixed-effects models; stochastic dynamic models; Bayesian inference;

    Abstract : To survive in environments with constantly changing nutrient levels the bud- ding yeast Saccharomyces cerevisiae has a sophisticated nutrient sensing system. A central component of this system is the SNF1 signalling pathway, which primarily helps yeast adapt to glucose limited conditions. READ MORE

  5. 8. DNA repair and genome organisation in mammalian cells : studies involving single-cell electrophoresis

    Author : Stefan Eriksson; Bert van Zeeland; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physical Biology; fysikalisk biologi;

    Abstract : The comet assay (single-cell electrophoresis) is a comparably new method for measurement of DNA strand breakage, primarily in eukaryotic cells. Its main advantage is that it works on the single-cell level, making it possible to detect heterogeneity in DNA damage induction and repair. READ MORE

  6. 9. Microtechnologies for single cell studies

    Author : Xu Shijun; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : .... READ MORE

  7. 10. Tumor cell heterogeneity profiling using single-cell analysis

    Author : Emma Jonasson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tumor heterogeneity; single-cell analysis; cancer stem cells;

    Abstract : Cancer is a diverse disease with large variations between tumor types and patients regarding tumor progression and prognosis. Additionally, most individual tumors are heterogeneous, containing subpopulations of cells with various characteristics. READ MORE