Search for dissertations about: "single-molecule imaging"

Showing result 16 - 20 of 35 swedish dissertations containing the words single-molecule imaging.

  2. 16. Assay development for studies of G protein-coupled receptors at the single-molecule level

    Author : Olov Wahlsten; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TIRF microscopy; colocalization; drug discovery; QCM-D; GPCR; pharmacodynamics; kinetics; equilibrium fluctuation analysis;

    Abstract : G protein-coupled receptors (GPCRs), also known as seven transmembrane (7TM) receptors,is the largest family of cell surface receptors. These receptors play a key role in transmittinga wide variety of signals across the cell membrane and are involved in physiologicalprocesses such as sensory transduction, cell-cell communication, neuronal transmission,and hormonal signaling. READ MORE

  4. 17. Raman and Fluorescence Spectroscopy of Single Molecules and Metal Particles

    Author : Jerk Bjerneld; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; laser-induced; single-molecule spectroscopy; surface-enhanced Raman scattering; nanoparticles;

    Abstract : Technological and conceptual advances have led to the realization of single-molecule spectroscopy. This permit detailed investigations of heterogeneous systems in fields ranging from condensed matter physics to biochemistry. It was recently discovered that surface-enhanced Raman scattering (SERS) can be used to study single molecules. READ MORE

  5. 18. Development and application of ultra-sensitive fluorescence spectroscopy and microscopy for biomolecular interaction studies

    Author : Lei Xu; Jerker Widengren; Gerhard Schütz; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; single molecule spectroscopy; fluorescence correlation spectroscopy; stimulated emission microscopy; cancer; biomolecular interaction; co-localization; Biological Physics; Biologisk fysik;

    Abstract : This thesis describes the development of sensitive and high-resolution fluorescence spectroscopic and microscopic techniques and their application to probe biomolecules and their interactions in solution, lipid membrane model systems and in cells. Paper I-IV are largely focused on methodological developments. READ MORE

  6. 19. Super-resolution Luminescence Micro-Spectroscopy : A nano-scale view of solar cell material photophysics

    Author : Aboma Merdasa; Kemisk fysik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; super-resolution microscopy; Single Molecule Spectroscopy; J-aggregates; perovskites; photophysics;

    Abstract : Optical microscopy is a fundamental tool in a range of disciplines encompassed by the physical and biological sciences. At the dawn of this millennium, a break-through was made in optical microscopy where super-resolution methods emerged and declared imaging beyond the optical diffraction limit a possibility. READ MORE

  7. 20. Super resolution fluorescence imaging : analyses, simulations and applications

    Author : Jan Bergstrand; Jerker Widengren; Eilon Sherman; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physics; Fysik;

    Abstract : Fluorescence methods offer extraordinary sensitivity and specificity, and are extensively used in the life sciences. In recent years, super resolution fluorescence imaging techniques have developed strongly, uniquely combining ~10 nm sub diffraction resolution and specific labeling with high efficiency. READ MORE