Search for dissertations about: "single-stranded overhang"

Found 3 swedish dissertations containing the words single-stranded overhang.

  2. 1. Functional Studies of Telomere-Binding Proteins in Saccharomyces castellii

    Author : Jenny Rhodin; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Rap1; DNA-binding domain; telomere evolution; Cdc13; telomerase; single-stranded overhang; telomere; yeast; Naumovia castellii; Saccharomyces castellii;

    Abstract : Telomeres are the ends of linear eukaryotic chromosomes. The telomeres are essential for solving the end replication problem and they stabilize the genome by protection from degradation. The telomeres also protect the chromosomal ends from by being recognized as DNA breaks by the repair machinery, which could lead to end-to-end fusions. READ MORE

  4. 2. Telomeric DNA in Chironomus, a naturally telomerase-free system

    Author : Monika Rosén; Udo Häckers grupp Utvecklingsbiologi i invertebrater; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; Chironomus; extrachromosomal telomeric repeats; RNA-DNA complex; 3´overhang; telocentric chromosome end; Telomere; complex repeats; Biologi; Genetics; cytogenetics; Genetik; cytogenetik;

    Abstract : Telomeres are specialized complexes of DNA and associated proteins that protect the ends of eukaryotic chromosomes. Although most organisms have short repeated DNA sequences at their telomeres, which are specified and maintained by the enzyme telomerase, there are a few exceptions. READ MORE

  5. 3. The maintenance of telomeres in the budding yeast Naumovozyma castellii

    Author : Humberto Itriago; Molekylär cellbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Telomere; Telomere dynamics; Telomere-Binding Proteins; Cdc13; Rap1; RAD52; Rad51; Homologous recombination; ALT; Budding yeast; Naumovozyma castellii;

    Abstract : Linear chromosomes of eukaryotic cells require the presence of functional nucleoprotein terminal structures, known as telomeres, to protect the integrity of the genome. The telomere is a highly dynamic and regulated structure constituted by short tandem DNA repeats rich in guanine nucleotides that extent as double-stranded DNA ending in a single-stranded 3′ overhang. READ MORE