Search for dissertations about: "site specificity"

Showing result 6 - 10 of 221 swedish dissertations containing the words site specificity.

2. 6. Lipase Specificity and Selectivity : Engineering, Kinetics and Applied Catalysis

   Author : Mohamad Takwa; Karl Hult; Bernhard Hauer; KTH; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Biokemi;

   Abstract : The specificity and selectivity of the enzyme Candida antarctica lipase B (CALB) were studiedfor several substrates and applications.With help of molecular modeling, the active site of CALB was redesigned for the ring openingpolymerization of D,D‐lactide. READ MORE

4. 7. Mechanisms and DNA Specificity in Site-specific Recombination of Integron Cassettes

   Author : Carolina Johansson; Lars Sundström; Dan Andersson; Didier Mazel; Uppsala universitet; []
   Keywords : Microbiology; lateral gene transfer; site-specific recombination; tyrosine recombinase; integron; single-stranded; DNA hairpin; Mikrobiologi; farmaceutisk mikrobiologi; Pharmaceutical Microbiology;

   Abstract : Bacterial resistance to antibiotics has become a serious problem. This is due to the remarkable ability of bacteria to respond and rapidly adapt to environmental changes. Integrons are elements with the capacity for gene capture by an integron-encoded site-specific recombinase called IntI. READ MORE

5. 8. Single-photon multiple ionisation of atoms and molecules investigated by coincidence spectroscopy : Site-specific effects in acetaldehyde and carbon dioxide

   Author : Sergey Zagorodskikh; Raimund Feifel; Vitali Zhaunerchyk; Melanie Mucke; Maria Novella Piancastelli; Tom Field; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; acetaldehyde; carbon dioxide; xenon; electron correlation; double ionisation; triple ionisation; core-valence ionisation; site-specific Auger decay; multiple Auger decay; branching ratios; site-specific photodissociation; molecular rearrangement; time-of-flight multi-electron-ion coincidence spectroscopy; synchrotron radiation; Physics with spec. in Atomic; Molecular and Condensed Matter Physics; Fysik med inriktning mot atom- molekyl- och kondenserande materiens fysik;

   Abstract : In this thesis, multiple ionisation processes of free atoms and molecules upon single photon absorption are studied by means of a versatile multi-electron-ion coincidence spectroscopy method based on a magnetic bottle, primarily in combination with synchrotron radiation. The latter offered the possibility to access not only valence but also core levels, revealing processes, which promote the target systems into different charge states. READ MORE

6. 9. Engineering carbonic anhydrase for highly selective ester hydrolysis

   Author : Gunnar Höst; Bengt-Harald Jonsson; Lars-Göran Mårtensson; Per Berglund; Linköpings universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; carbonic anhydrase; specificity; hydrolysis; rational design; protein engineering; plasmodium falciparum; Bioengineering; Bioteknik;

   Abstract : I denna avhandling presenteras arbete utfört med enzymet humant karboanhydras II (HCAII). Enzymer är en typ av proteiner som accelererar (katalyserar) kemiska reaktioner, vilket är nödvändigt för allt levande. Den naturliga funktionen för HCAII är att katalysera omvandlingen av gasen koldioxid till vätekarbonat, som är löslig i vätska. READ MORE

7. 10. Exploiting enzyme promiscuity for rational design

   Author : Cecilia Branneby; Karl Hult; Alex Zaks; KTH; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Candida antarctica lipase B; alanine racemase; substrate specificity; reaction specificity; enzyme catalytic promiscuity; Biokemi; Biochemistry; Biokemi;

   Abstract : Enzymes are today well recognized in various industrial applications, being an important component in detergents, and catalysts in the production of agrochemicals, foods, pharmaceuticals, and fine chemicals. Their large use is mainly due to their high selectivity and environmental advantage, compared to traditional catalysts. READ MORE