Search for dissertations about: "skin biopsy specimens"

Found 5 swedish dissertations containing the words skin biopsy specimens.

  1. 1. Minimally-invasive breast interventions : methods for high yield, low risk, precision biopsy and curative thermal ablation

    Author : Kai-Uwe Schässburger; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Advances in medical imaging and the introduction of population-based screening programs have increased the detection rate and overall proportion of small breast tumors. In addition, progress in technology and medical science, in combination with efforts to minimize morbidity, have resulted in the emergence of minimally invasive image-guided interventional procedures for both diagnosis and treatment of breast cancer. READ MORE

  2. 2. Immunological mechanisms in atopic dermatitis : clinical and experimental studies

    Author : Maria Tengvall Linder; Karolinska Institutet; Karolinska Institutet; []
    Keywords : atopic dermatitis; Cyclosporin A; cytokines; eosinophils; lgE; lgE receptors; Pityrosporum orbiculare; patch test; skin biopsy specimens; T cells;

    Abstract : The aim of the study was to investigate immunological mechanisms in atopic dermatitis. Serum IgE levels are elevated in 80% of atopic dermatitis patients and CD4+ T cells and environmental allergens are known to be of importance in the pathogenesis of the disease. READ MORE

  3. 3. Analysis of human epidermal Langerhans' cells and allergens with confocal laser scanning microscopy

    Author : Axel Emilson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : 3-D analysis; allergen; allergic contact dermatitis; basal cellcarcinoma; Bet v I; birch; confocal laser scanning microscopy; epidermis; HLA-DR; image analysis; invariant chain; irritant contact dermatitis; Langerhans cell; occlusion; P. orbiculare;

    Abstract : The aim of the thesis was to explore confocal laser scanning microscopy (CLSM) as a tool for 1) quantitative and 3-dimensional (3-D) analysis of the human antigen-presenting Langerhans' cell (LC) in epidermis and 2) for localization of allergens in yeast cells and in birch pollen. Epidermal LCs were investigated after occlusion with patch tests and in basal cell carcinoma (BCC) skin. READ MORE

  4. 4. Studies on molecular regulation of inflammation in cutaneous lupus erythematosus

    Author : Vilija Oke; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Lupus erythematosus (LE) is an autoimmune disease with a wide range of clinical manifestations. This spectrum spans from limited cutaneous disease to life-threatening rheumatic disorder involving vital organs. Sun exposure is an evident exogenous trigger of both cutaneous (CLE) and systemic LE (SLE). READ MORE

  5. 5. Botulinum Toxin in the Treatment of Focal Hyperhidrosis and Dyshidrotic Hand Dermatitis

    Author : Carl Swartling; Klas Nordlind; Uppsala universitet; []
    Keywords : Medical sciences; Hyperhidrosis; dyshidrotic hand dermatitis; botulinum toxin; side-effects; EMG; quality of life; sweat glands; immunohistochemistry; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Dermatologi och venereologi; Dermatology and Venerology;

    Abstract : Excessive sweating may cause considerable disability, with psychological, social and occupational consequences. Primary hyperhidrosis may also play a key role in the pathogenesis of dyshidrotic dermatitis and some other skin diseases. READ MORE