Search for dissertations about: "skov 3"

Showing result 1 - 5 of 16 swedish dissertations containing the words skov 3.

  2. 1. In vitro analyses of immune responses to metal and organic haptens in humans with contact allergy

    Author : Khosro Masjedi; Marita Troye-Blomberg; Niklas Ahlborg; Lone Skov; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ELISpot; contact allergy; parthenolide; methylisothiazolinones; nickel; hapten; Allergology; Allergologi; immunologi; Immunology;

    Abstract : Contact allergy is one of the most common skin diseases with great social and economical impact. The origin and nature of contact allergens (haptens) capable of inducing T-cell mediated allergic reactions are diverse, ranging from organic molecules to metal ions. READ MORE

  4. 2. Mechanisms for immune escape in epithelial ovarian cancer

    Author : Pernilla Israelsson; Ulrika Ottander; Lucia Mincheva-Nilsson; Eva Lundin; Ivan Nagaev; Karin Sundfeldt; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human; ovarian cancer; high-grade serous cancer; EOC; HGSC; HGSOC; tumor microenvironment; immune escape; immune suppression; cytokines; exosomes; NKG2D; MICA B; ULBP1-3; DNAM-1; surgery; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Tumors develop mechanisms to subvert the immune system, constituting immune escape. Epithelial ovarian cancer (EOC), the deadliest of all gynecological malignancies, uses a variety of mechanisms to undermine immune surveillance, aiding its establishment and metastatic spreading. READ MORE

  5. 3. The Balance between Pro- and Antiinflammatory Molecules in ANCA-Associated Vasculitis

    Author : Sophie Ohlsson; Njurmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nephrology; Urologi; nefrologi; Urology; monocyte; SLPI; proteinase 3; ANCA; vasculitis; inflammation;

    Abstract : ANCA-associated systemic vasculitis (AASV) is a group of inflammatory disorders, characterized by inflammation and necrosis of blood vessels and frequently granuloma formation. Patients with AASV make autoantibodies, so called ANCA, against proteins present in the granules of neutrophils and monocytes, mainly proteinase 3 (PR3) and myeloperoxidase (MPO). READ MORE

  6. 4. Engineering of alternative scaffold derived drug conjugates and fusion-toxins for targeted cancer therapy

    Author : Wen Yin; Torbjörn Gräslund; Serge Muyldermans; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; HER2; Affibody; Cancer; ADAPT; Protein engineering; PE38; DM1; MMAE; MMAF; Biotechnology; Bioteknologi;

    Abstract : Cancer is a major health problem, with premature death for many patients, and with a high monetary cost to society. The disease is complex to treat due to the many different types, but also because the disease-causing cells, that needs to be removed, are very similar to the normal cells. READ MORE

  7. 5. Rational and combinatorial protein engineering for vaccine delivery and drug targeting

    Author : Maria Wikman; Stefan Ståhl; Carl A. K. Borrebaeck; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicine; affibody; affinity chromatography; biotin; combinatorial; delivery; phage display; Biomedicin; Microbiology; Mikrobiologi;

    Abstract : This thesis describes recombinant proteins that have been generated by rational and combinatorial protein engineering strategies for use in subunit vaccine delivery and tumor targeting.In a first series of studies, recombinant methods for incorporating immunogens into an adjuvant formulation, e.g. READ MORE