Search for dissertations about: "sle management thesis"

Showing result 1 - 5 of 9 swedish dissertations containing the words sle management thesis.

  2. 1. Defining the genetics of systemic autoimmunity in mouse models of lupus

    Author : Katarina Haraldsson; Kristina Lejon; Dwight Kono; Chandra Mohan; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; SLE; susceptibility; HgIA; genome-wide mapping; Lbw2; Lmb1-4; suppressing gene; Immunology; Immunologi;

    Abstract : Systemic Lupus Erythematosus (SLE) is a chronic multi-organ autoimmune disease considered a prototype for autoantibody and immune complex-mediated tissue injury. Although autoantibodies against a wide diversity of self-antigens are characteristically found in this disease, an important hallmark is the presence of autoantibodies to nuclear antigens. READ MORE

  4. 2. Health economic aspects of diabetic retinopathy

    Author : Emelie Heintz; Lars-Åke Levin; Ann-Britt Wiréhn; Josephine Mauskopf; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetes; diabetic retinopathy; health economic evaluations; quality-adjusted life years; costs; quality of life; prevalence;

    Abstract : To ensure that the resources of the health care sector are used effectively, new technologies need to be evaluated before implementation to examine if they generate health outcomes at an acceptable cost. This information can be collected by performing health economic evaluations in which the costs and health outcomes of different technologies are compared. READ MORE

  5. 3. Studies on anti-dsDNA Antibodies and other potential biomarkers in Systemic Lupus Erythematosus

    Author : Michele Compagno; Reumatologi och molekylär skelettbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic Lupus Erythematosus Anti-dsDNA antibodies Biomarkers Osteopontin S100A8 A9 LE-cells Diagnostic accuracy Longitudinal study Multicentre study;

    Abstract : Systemic Lupus Erythematosus (SLE) is characterized by chronic inflammation involving many organ systems. The etiology is unknown and the pathogenesis has not been fully elucidated. Impairments of the immune system and of the mechanisms regulating cell death are commonly seen in SLE patients. READ MORE

  6. 4. Biomarkers and mediators in systemic lupus erythematosus : IFNα versus the CRP response, and evaluation of suPAR and anti-dsDNA antibody assays

    Author : Helena Enocsson; Jonas Wetterö; Thomas Skogh; Christopher Sjöwall; Søren Jacobsen; Linköpings universitet; []
    Keywords : ;

    Abstract : Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease which may affect multiple organ systems. Interferon alpha (IFNα) and autoantibodies that form immune complexes with nuclear antigens (ANA) are hallmarks believed to drive the disease into a vicious circle of inflammation, tissue damage, autoantigen exposure and autoantibody production. READ MORE

  7. 5. Systemic lupus erythematosus : biomarkers and biologics

    Author : Ioannis Parodis; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Systemic lupus erythematosus (SLE) is a chronic autoimmune disease, predominantly affecting women of childbearing age. The pathogenesis of SLE is multifactorial, and the clinical phenotype and course vary considerably within the SLE population. Multiple organs can be involved, lupus nephritis (LN) being one of the most severe manifestations. READ MORE