Search for dissertations about: "slowly-progressive"

Showing result 11 - 15 of 20 swedish dissertations containing the word slowly-progressive.

  2. 11. Disability and physical exercise in adults with myotonic dystrophy type 1

    Author : Marie Kierkegaard; Karolinska Institutet; Karolinska Institutet; []
    Keywords : classification;

    Abstract : Background: Myotonic dystrophy type 1(DM1) is an inherited, slowly progressive, multi-system disease. There is no overall picture of its effect in individuals, and there is a lack of scientific evidence to support recommendations on physical exercise. READ MORE

  4. 12. Orofacial dysfunctions in children and adolescents with myotonic dystrophy type 1 - evaluation and intervention

    Author : Lotta Sjögreen; Göteborgs universitet; []
    Keywords : myotonic dystrophy type 1; children; facial expression; dysarthria; dysphagia; drooling; lip force; lip mobility; 3D motion analysis; oral screen;

    Abstract : Myotonic dystrophy type 1 (DM1) is a slowly progressive neuromuscular disease. The overall aim of this thesis was primarily to describe the characteristics, prevalence, and development of orofacial functions in a group of children and adolescents with DM1 and secondly to investigate the effect of lip strengthening exercises. READ MORE

  5. 13. Cerebral CT - and MRI perfusion: Techniques and clinical application in iNPH

    Author : Doerthe Ziegelitz; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cerebral perfusion; idiopathic normal pressure hydrocephalus; computed tomography perfusion; dynamic suceptibility contrast MRI;

    Abstract : Idiopathic normal pressure hydrocephalus (iNPH) is a disorder of the elderly, defined by slowly progressive impairment of gait and balance, cognitive decline, and incontinence. Disturbance of the cerebrospinal fluid (CSF) dynamics results in ventriculomegaly without intracranial pressure increase. READ MORE

  6. 14. Coreceptor usage and sensitivity to neutralization of HIV-1 and HIV-2

    Author : Yu Shi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : HIV-1; HIV-2; pathogenesis; neutralization; coreceptor usage; envelop sequence; glycosylation; U87.CD4 cells; GHOST 3 cells; CCR5; CXCR4;

    Abstract : The aim of this project was to study neutralization and coreceptor use in HIV-1 and HIV-2. The first step was to develop a simple and standardized assay for detection and quantification of HIV- 1 neutralizing activity in human sera. READ MORE

  7. 15. Cryptogenic Polyneuropathy : Clinical, Environmental, And Genetic Studies

    Author : Jonas Lindh; Magnus Vrethem; Göran Solders; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuropathy; Neurology; Neurologi;

    Abstract : Objectives: The purpose of this medical thesis was to describe the clinical and neurophysiological features and to evaluate the health related quality of life (HR-QoL) in patients with cryptogenic polyneuropathy. We also wanted to investigate different occupational, and leisure time exposures as determinants for cryptogenic polyneuropathy, and to analyze whether polymorphisms for the null alleles of Glutathione S-Transferase Mu-1 (GSTM1), and Theta-1 (GSTT1), and a low activity genetic variation of epoxide hydrolase (EPHX) affect the risk of developing polyneuropathy. READ MORE