Search for dissertations about: "small RNA"

Showing result 21 - 25 of 315 swedish dissertations containing the words small RNA.

  2. 21. The deep evolutionary roots of non-coding RNA - a comparative genomics approach

    Author : Marc Patrick Hoeppner; Anthony M. Poole; Britt-Marie Sjöberg; Jürgen Brosius; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; non-coding RNA; evolution; comparative genomics; RNA world; introns; snoRNA; miRNA; Molecular biology; Molekylärbiologi; Molecular Biology; molekylärbiologi;

    Abstract : Non-coding RNAs (ncRNA) are a diverse group of genes that do not encode proteins but function exclusively on the level of RNA and were originally suggested to be remnants of a pre-DNA stage of life known as the RNA world. More recent work, however, has uncovered a rich repertoire of previously unknown families with possible consequences for our understanding of the origin and evolution of the modern RNA infrastructure. READ MORE

  4. 22. Regulatory roles of two small RNAs in the human pathogen Listeria monocytogenes and the evaluation of an alternative infection model

    Author : Jonas Gripenland; Jörgen Johansson; Tom Geissmann; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; small RNA; sRNA; Riboswitch; Listeria monocytogenes; ncRNA; PrfA; molekylärbiologi; Molecular Biology;

    Abstract : Listeriosis is a potentially lethal disease caused by the Gram-positive facultative intracellular pathogen Listeria monocytogenes (L.m.). L. READ MORE

  5. 23. Small non-coding RNA in early fly development : plasticity, interactions and improved bioinformatic tools

    Author : Lovisa Örkenby; Anita Öst; Rashmi Ramesh; Daniel Nätt; Nicola Iovino; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Drosophila; Maternal-to-zygotic transition; sncRNA; miRNA; piRNA; Embryogenesis; Zygotic gene activation;

    Abstract : At fertilization, the male and female pronuclei undergo a transformation from germline to pluripotency as they fuse, marking the beginning of Drosophila embryogenesis. As the parental contributions decrease, the zygote takes control of its genome in a process called the maternal-to-zygotic transition (MZT). READ MORE

  6. 24. Small non-coding RNAs in cancer

    Author : Helena Persson; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microRNA; non-coding RNA; breast cancer; CYP3A4; bladder cancer;

    Abstract : The complex genetics of cancer, which allows tumours to grow and spread while bypassing the control circuitry of the cell, involves dysregulation of the genome, transcriptome and proteome. The importance of protein-coding genes such as growth factors and hormone receptors is well established. READ MORE

  7. 25. Biology of a small RNA virus that infects Drosophila melanogaster

    Author : Sajna Anand Sadanandan; Dan Hultmark; Francis Jiggins; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nora virus; Drosophila melanogaster; virus biology; host-pathogen interaction; molekylärbiologi; Molecular Biology;

    Abstract : Drosophila melanogaster has been extensively used as a model organism to study diverse facets of biology, including host-pathogen interactions and the basic biology of its pathogens. I have used the fruit fly as a model to study elementary aspects of Nora virus biology, such as the role of the different proteins encoded by the virus genome. READ MORE