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Showing result 1 - 5 of 103 swedish dissertations matching the above criteria.
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1. Small RNAs, Big Consequences : Post-transcriptional Regulation and Adaptive Immunity in Bacteria
Abstract : It is nowadays widely accepted that non-coding RNAs play important roles in post-transcriptional regulation of genes in all kingdoms of life. In bacteria, the largest group of RNA regulators are the small RNAs (sRNAs). READ MORE
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2. Adenoviral small non-coding RNAs : A Structural and Functional Charaterization
Abstract : Since their discovery in 1953, adenoviruses have significantly contributed to the understanding of virus-host cell interactions, including mechanistic details of cellular processes such as cell cycle control and alternative RNA splicing. Among the first characterized adenoviral genes were the virus-associated RNAs (VA RNAI/II), which are produced in massive amount during a lytic infection. READ MORE
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3. Macromolecular Matchmaking : Mechanisms and Biology of Bacterial Small RNAs
Abstract : Cells sense the properties of the surrounding environment and convert this information into changes in gene expression. Bacteria are, in contrast to many multi-cellular eukaryotes, remarkable in their ability to cope with rapid environmental changes and to endure harsh and extreme milieus. READ MORE
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4. Function and Evolution of Small Regulatory RNAs and their Associated Proteins : A Journey from Genome to Proteome
Abstract : Organisms throughout the tree of life have evolved distinct ways to regulate gene expression. Some of these processes involve non-coding RNAs (ncRNAs), which are not translated but functional nonetheless. These ncRNAs are of utmost importance, with dysregulation of some causing severe developmental effects or even being lethal. READ MORE
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5. Small non-coding RNAs in cancer
Abstract : The complex genetics of cancer, which allows tumours to grow and spread while bypassing the control circuitry of the cell, involves dysregulation of the genome, transcriptome and proteome. The importance of protein-coding genes such as growth factors and hormone receptors is well established. READ MORE