Search for dissertations about: "small RNAs"

Showing result 21 - 25 of 103 swedish dissertations containing the words small RNAs.

  2. 21. Regulation of skeletal muscle metabolism and development by small, non-coding RNAs : implications for insulin resistance and type 2 diabetes mellitus

    Author : Rasmus Sjögren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : microRNAs (miRNAs) are a class of epigenetic post-transcriptional regulators. These short (~22 nucleotides) non-coding RNAs can potently reduce protein abundance through direction of the RNA-induced silencing complex to targeted genes. READ MORE

  4. 22. Understanding the role of regulatory RNAs in human skin wound healing

    Author : Letian Zhang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Human skin wound healing is characterized by four phases in a timely manner, including hemostasis, inflammation, proliferation, and remodeling. Various cell types are involved in the biological process. READ MORE

  5. 23. Understanding the role of non-coding RNAs in skin homeostasis and cancer

    Author : Kunal Das Mahapatra; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The epidermis is a stratified epithelium with continuous self-renewing capacity. As the outermost layer of our body, it provides a protective barrier against external trauma, produces pigmentation, and keeps the skin hydrated. Keratinocytes are the primary constituent cells type within the epidermis. READ MORE

  6. 24. Genomic and functional analysis of microRNAs and PIWI-interacting RNAs in human cancers

    Author : Mahmut Deniz Özata; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Small non-coding RNAs, including microRNAs (miRNAs) and piwi-interacting RNAs (piRNAs), play an important role in gene expression regulation and are involved in many biological and pathological processes. Study of small RNA expression and function in cancer cells could contribute to greater understanding of how small RNAs are involved in cancer development. READ MORE

  7. 25. Little strokes fell great oaks : small RNA in potato and Phytophthora infestans interactions

    Author : Kristian Persson Hodén; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Abstract : Small RNAs (sRNAs) are non-coding RNAs of approximately 20-30 nucleotides in length. sRNAs bind to Argonaute proteins (AGOs) an integrated partner of the RISC complex. sRNAs act as templates for RISC to recognize complementary mRNA transcripts which can be cleaved by AGOs and thereby cause gene inactivity. READ MORE