Search for dissertations about: "small intestinal neuroendocrine tumours"

Showing result 1 - 5 of 9 swedish dissertations containing the words small intestinal neuroendocrine tumours.

  1. 1. Small Intestinal Neuroendocrine Tumours : Genetic and Epigenetic Studies and Novel Serum Biomarkers

    Author : Katarina Edfeldt; Peter Stålberg; Per Hellman; Gunnar Westin; Malin Sund; Endokrinkirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SI-NET; microarray; tumour suppressor gene; epigenetic; serum biomarkers; Kirurgi; Surgery;

    Abstract : Small intestinal neuroendocrine tumours (SI-NETs) are rare, hormone producing and proliferate slowly. Patients usually display metastases at time of diagnosis, the tumours are difficult to cure, and the disease course is unpredictable. READ MORE

  2. 2. Small intestinal neuroendocrine tumours - Disease models, tumour development, and remedy

    Author : Tobias Hofving; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroendocrine tumours; tumour models; SMAD4; 177Lu-octreotate therapy; immunotherapy;

    Abstract : Small intestinal neuroendocrine tumours (SINETs) are malignant neoplasms which at the time of diagnosis often present with distant metastasis. The field of SINET research faces several challenges. READ MORE

  3. 3. Prognostic Factors for Death in Small Intestinal Neuroendocrine Tumours

    Author : John Eriksson; Per Hellman; Kjetil Søreide; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; SI-NET; Prognostication; Immunohistochemistry; Surgery; Kirurgi;

    Abstract : Tumours in the small intestine are rare compared to those in other gastrointestinal organs. Small intestinal neuroendocrine tumours (SI-NETs) are the most common small bowel tumours with an annual incidence of 0.3-1.7 per 100 000 persons. READ MORE

  4. 4. Peptide Receptor Radionuclide Therapy in Neuroendocrine Neoplasms : Aspects of tumour characteristics, receptor recycling and peptide mass

    Author : Ulrika Jahn; Anders Sundin; Mark Lubberink; Ulrike Garske-Román; Mona-Elisabeth Rootwelt-Revheim; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroendocrine tumors; Peptide receptor radionuclide therapy PRRT ; Peptide; Small-Intestinal; Pancreatic; Dosimetry; Somatostatin receptor;

    Abstract : Neuroendocrine neoplasm (NEN) can arise in any part of the body, but most commonly in the lungs, bronchi, and the gastrointestinal tract including the pancreas. They combine neuroendocrine and tissue-of-origin-specific characteristics; explaining different symptoms depending on the organ of origin. READ MORE

  5. 5. Targeted radiotherapy in metastatic neuroendocrine tumours: clinical and experimental studies

    Author : Anna-Karin Elf; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroendocrine tumour; peptide receptor radionuclide therapy; somatostatin receptor 2 expression; radiosensitization; radioembolization; diffusion weighted imaging;

    Abstract : ABSTRACT Neuroendocrine tumours (NET) often present at a metastatic stage, which diminishes the possibility for curative surgery. Peptide receptor radiotherapy (PRRT) with 177Lu-DOTATATE targets somatostatin receptors, which are overexpressed on NET cells. PRRT results in symptom relief and often tumour control of NETs, but rarely cure. READ MORE