Search for dissertations about: "small molecule."

Showing result 1 - 5 of 427 swedish dissertations containing the words small molecule..

  1. 1. Design, Synthesis and Characterization of Small Molecule Inhibitors and Small Molecule Peptide Conjugates as Protein Actors

    University dissertation from Institutionen för fysik, kemi och biologi

    Author : Jonas Nilsson; Lars Baltzer; Ingemar Kvarnström; Thomas Olsson; [2005]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Synthetic receptor; Peptide inhibitor conjugate; Peptide protein surface interactions; General Lead Discovery Library; Combinatorial Chemistry; Solid Phase Chemistry; Targeted Library; Thrombin inhibitor; Fluorescence; Surface Plasmon Resonance; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Abstract : This thesis describes different aspects of protein interactions. Initially the function of peptides and their conjugates with small molecule inhibitors on the surface of Human Carbonic Anhydrase isoenzyme II (HCAII) is evaluated. READ MORE

  2. 2. Small Molecule Diffusion in Spherulitic Polyethylene Experimental Results and Simulations

    University dissertation from Stockholm : KTH

    Author : Alessandro Mattozzi; Ulf W. Gedde; Alan H. Windle; [2006]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; diffusion; polyethylene; poly ethylene-co-octene ; free volume; morphology; intermediate phase; spherulite; Monte Carlo simulation; NATURAL SCIENCES Chemistry Organic chemistry Polymer chemistry; NATURVETENSKAP Kemi Organisk kemi Polymerkemi;

    Abstract : The diffusion of small-molecule penetrants in polyethylene is hindered by impenetrable crystals and by the segmental constraints imposed by the crystals on the penetrable phase. Liquid and vapour n-hexane sorption/desorption measurements were performed on metallocene catalyzed homogenous poly(ethylene-co-octene)s. READ MORE

  3. 3. Small molecule diffusion in spherulitic polyethylene : experimental results and simulations

    University dissertation from Stockholm : KTH

    Author : Alessandro Mattozzi; [2004]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES Chemistry Organic chemistry Polymer chemistry; NATURVETENSKAP Kemi Organisk kemi Polymerkemi;

    Abstract : .... READ MORE

  4. 4. Small-molecule layers for devices –Evaporation growth

    University dissertation from Stockholm : KTH

    Author : Måns Andreasson; [2005]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Abstract : .... READ MORE

  5. 5. Chemical attenuation of bacterial virulence small molecule inhibitors of type III secretion

    University dissertation from Umeå : Kemi

    Author : Anna Kauppi; Mikael Elofsson; Anders Karlén; [2006]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; antibiotic resistance; virulence; type III secretion; T3SS inhibitors; Yop; SMD; QSAR; screening; Yersinia pseudotuberculosis; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Abstract : Despite the large arsenal of antibiotics available on the market, treatment of bacterial infections becomes more challenging in view of the fact that microbes develop resistance against existing drugs. There is an obvious need for novel drugs acting on both old and new targets in bacteria. READ MORE