Search for dissertations about: "small molecules"

Showing result 21 - 25 of 860 swedish dissertations containing the words small molecules.

  1. 21. Bifunctionalization of Small Organic Molecules Based on Fluorine Incorporation

    Author : Marvin Lübcke; Kálmán Szabó; Ryan Gilmour; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; fluorination; fluorocyclization; fluorine chemistry; trifluoromethylthiolation; rhodium-catalysis; organocatalysis; asymmetric synthesis; hypervalent iodine; multicomponent reaction; bifunctionalization; diazo compounds; organisk kemi; Organic Chemistry;

    Abstract : The dissertation work that is summarized in this thesis describes novel syntheses of organofluorine compounds with a broad coverage of different fluorine-containing motifs.Chapter 2.1 covers works on the exploration of new trifluoromethylthiolating reactions of diazocarbonyl compounds. READ MORE

  2. 22. Physicochemical Characterisation of Small Drug Molecules by Capillary Electrophoresis

    Author : Eivor Örnskov; Uppsala universitet; []
    Keywords : ;

    Abstract : .... READ MORE

  3. 23. Selective induction of apoptosis in tumors by small molecules reactivating p53

    Author : Natalia Issaeva; Karolinska Institutet; Karolinska Institutet; []
    Keywords : p53; HDM2; reactivation; apoptosis; tumors; small molecule.;

    Abstract : Lesions in the p53 pathway that inactivate p53 tumor suppression function occur with extremely high frequency in cancer, targeting almost all tumors regardless of patient age or tumor type. This study is aimed at developing approaches for the selective elimination of tumors carrying defects in the p53 pathway, namely protection of p53 from degradation by its own destructor HDM2 in wild type p53-carrying tumors and refolding of p53 by small molecules in mutant p53-containing tumors. READ MORE

  4. 24. Quantum transport in photoswitching molecules : An investigation based on ab initio calculations and Non Equilibrium Green Function theory

    Author : Anders Odell; Anna Delin; Anders Niklasson; Jonas Fransson; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; molecular electronics; electron transport; electron structure; density functional theory; non equilibrium green function theory; Electronic structure; Elektronstruktur;

    Abstract : Molecular electronics is envisioned as a possible next step in device miniaturization. It is usually taken to mean the design and manufacturing of electronic devices and applications where organic molecules work as the fundamental functioning unit. READ MORE

  5. 25. Metal Cluster Reactivity. Adsorption of small molecules in biomolecular collisions

    Author : Mats Andersson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; O2; CO; ionization potential; Con; Fen; NO; sticking probability; laser ionization; D2; Wn; Cun; Rhn; reaction probability; cluster; jellium model; Nbn; metal cluster reactivity; N2; time-of-flight mass spectrometry; Nin;

    Abstract : Metal clusters can be characterized as the tiniest possible metal particles, containing only an easily counted number of atoms. In this work, reactions between metal clusters and diatomic molecules have been investigated. We have constructed an experimental set-up to produce and detect clusters, and to investigate their chemical reactivity. READ MORE