Search for dissertations about: "smooth muscle differentiation"

Showing result 1 - 5 of 53 swedish dissertations containing the words smooth muscle differentiation.

2. 1. Transcriptome analysis on in vivo derived laser microbeam microdissected cells. Analysis of smooth muscle transcriptomes

   Author : Stefan Johannes Scheidl; Göteborgs universitet; []
   Keywords : microarray; laser microdissection; RNA amplification; smooth muscle cells; smooth muscle differentiation; smooth muscle transcriptome; smooth muscle diversity;

   Abstract : Smooth muscle cells (SMCs) are found in the respiratory, urogenital, circulatory and digestive systems. They provide contractility and structural support for those organs and perform multiple physiological important functions, such as modulation of blood pressure, regulation of airway resistance, and control of gastrointestinal and genitourinary motility. READ MORE

4. 2. A genomic approach to smooth muscle differentiation and diversity

   Author : Sven Nelander; Göteborgs universitet; []
   Keywords : Keywords: smooth muscle; phenotype; transcriptional regulation; differentiation; transcriptome; microarray; computational prediction; co-expression network; regulatory sequence analysis; gene module; gene battery;

   Abstract : Smooth muscle cells (SMCs) are a broad class of contractile cells that are found in a number of organs systems, including the vasculature, the urogenital system, the bronchi and the gastrointestinal tract. The two main functions exerted by SMCs are to provide contractile force and to synthesize structural components of the extracellular matrix. READ MORE

5. 3. Mechanisms of stretch-induced growth and contractile differentiation in vascular smooth muscle

   Author : Asad Zeidan; Institutionen för experimentell medicinsk vetenskap; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Fysiologi; Physiology; SM22a; ERK1 2; caveolae; stretch; Smooth muscle; differentiation;

   Abstract : Vascular smooth muscle can adapt to increased intraluminal pressure by remodelling and hypertrophy, as seen in hypertension. The molecular mechanisms responsible for this are still incompletely characterized. READ MORE

6. 4. Regulation of inducible nitric oxide synthase - Consequences in experimental models of bladder disease

   Author : Rebecka Johansson; Avdelningen för klinisk kemi och farmakologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacy; toxicology; Farmakologi; smooth muscle-myosin heavy chain; Pharmacological sciences; pharmacognosy; farmakognosi; farmaci; actin; BDNF; Rho; aminoguanidine; TNF-alpha; IL-1beta; hypertrophy; differentiation; smooth muscle; bladder; nitric oxide; inducible nitric oxide synthase; toxikologi;

   Abstract : Inducible nitric oxide synthase (iNOS) expression is associated with various pathophysiological conditions in the lower urinary tract. The aims of this thesis have been to investigate the regulation of iNOS in bladder smooth muscle cells and the consequences on neuromuscular regulation, cell growth and differentiation. READ MORE

7. 5. Regulation of the vascular smooth muscle cell phenotype

   Author : Henrik Lindskog; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; embryonic stem cells; vascular smooth muscle cell; smooth muscle cell; pericyte; phenotypic modulation; lipoma preferred partner; ectra-cellular matrix; zinc finger protein 148;

   Abstract : Smooth muscle cells (SMC) are present in many internal organs such as the blood vessels and the gastrointestinal channel. Their main functions are to provide stability to the tissue and to provide contractile capability. SMC are not terminally differentiated but can switch between several phenotypes, which is also known as phenotypic modulation. READ MORE