Search for dissertations about: "smooth muscle transcriptome"

Showing result 1 - 5 of 6 swedish dissertations containing the words smooth muscle transcriptome.

2. 1. Transcriptome analysis on in vivo derived laser microbeam microdissected cells. Analysis of smooth muscle transcriptomes

   Author : Stefan Johannes Scheidl; Göteborgs universitet; []
   Keywords : microarray; laser microdissection; RNA amplification; smooth muscle cells; smooth muscle differentiation; smooth muscle transcriptome; smooth muscle diversity;

   Abstract : Smooth muscle cells (SMCs) are found in the respiratory, urogenital, circulatory and digestive systems. They provide contractility and structural support for those organs and perform multiple physiological important functions, such as modulation of blood pressure, regulation of airway resistance, and control of gastrointestinal and genitourinary motility. READ MORE

4. 2. A genomic approach to smooth muscle differentiation and diversity

   Author : Sven Nelander; Göteborgs universitet; []
   Keywords : Keywords: smooth muscle; phenotype; transcriptional regulation; differentiation; transcriptome; microarray; computational prediction; co-expression network; regulatory sequence analysis; gene module; gene battery;

   Abstract : Smooth muscle cells (SMCs) are a broad class of contractile cells that are found in a number of organs systems, including the vasculature, the urogenital system, the bronchi and the gastrointestinal tract. The two main functions exerted by SMCs are to provide contractile force and to synthesize structural components of the extracellular matrix. READ MORE

5. 3. A functional genomics approach to PDGF and pericyte biology

   Author : Cecilia Bondjers; Göteborgs universitet; []
   Keywords : PDGF; hair follicle; skin; testis; epithelial-mesenchymal interaction; microarray; pericyte; transgenic mouse;

   Abstract : The rapid expansion of genome sequence data demands for increased efforts and speed concerning functional analysis of gene products. Two approaches to such analysis, namely transgenic technologies and analysis of gene expression have successfully been used to study functions of gene products in complex organisms, such as mammals. READ MORE

6. 4. Geometric, biomechanical and molecular analyses of abdominal aortic aneurysm

   Author : Moritz Lindquist Liljeqvist; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Background: Abdominal aortic aneurysm (AAA) is defined as a dilatation of the abdominal aorta of 30 mm in diameter or more. Main risk factors are smoking, age and male sex. Pathophysiological features include inflammation, smooth muscle cell loss and destruction of the extracellular matrix. READ MORE

7. 5. Functional analysis of genes in the developing zebrafish pronephros and vasculature

   Author : Lwaki Ebarasi; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : During glomerulogenesis, the recruitment and assembly of visceral epithelial cells (podocytes), endothelial capillary cells, and smooth muscle pericytes (mesangial cells) result in the formation of the glomerular tuft. The mature glomerulus functions by passage of plasma under hemodynamic pressure across a filter, the glomerular filtration barrier, and the integrity of the barrier is crucial for proper function. READ MORE