Search for dissertations about: "sodium cromoglycate"

Found 3 swedish dissertations containing the words sodium cromoglycate.

2. 1. Particles in small airways : mechanisms for deposition and clearance and pharmacokinetic assessments of delivered dose to the lung

   Author : Maria Lindström; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Lung deposition; clearance; small airways; pharmacokinetic; cystic fibrosis; primary ciliary dyskinesia; asthma; sodium cromoglycate;

   Abstract : BACKGROUND: Knowledge about lung deposition and clearance from airways of inhaled particles/drugs are essential for evaluation of health effects of inhaled pollutants and to achieve optimal drug dose to the lung. The primary defence mechanism in the conducting airways is the mucociliary clearance (MCC). READ MORE

4. 2. Studies of exercise-induced bronchoconstriction to define protective mechanisms in asthma

   Author : Johan Bood; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Exercise-induced bronchoconstriction (EIB) occurs in the majority of asthmatics following vigorous exercise. EIB is caused by a loss of water from the airways creating a hyperosmolar environment in the tissue that in turn triggers the release of bronchoconstrictive mediators. READ MORE

5. 3. Mast cell activation in response to osmotic and immunological stimulation with focus on release of eicosanoid mediators

   Author : Magdalena Gulliksson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Exercise-induced bronchoconstriction; cyclooxygenase; cord blood derived mast cells; mannitol; prostaglandin D2; leukotriene C4; leukotriene E4; histamine and 15-lipoxygenase.;

   Abstract : Mast cells are important in asthma and other inflammatory diseases. Subjects with asthma have been found to have an increased number of mast cells in their airway smooth muscle and this was related to airway sensitivity. READ MORE