Search for dissertations about: "sodium deficiency"

Showing result 1 - 5 of 12 swedish dissertations containing the words sodium deficiency.

  2. 1. The Role of Kidney Oxygen Homeostasis for the Development of Kidney Disease

    Author : Carla Carvalho; Fredrik Palm; Peter Hansell; Malou Friederich; Jenny Nyström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oxygen; Kidney mitochondria; Hypoxia-inducible factors; Prolyl hydroxylase; von Hippel-Lindau; Diabetes; Aging; Kidney; Sodium; RAAS; Fysiologi; Physiology;

    Abstract : The relation between oxygen supply and demand determines tissue oxygen tension (PO2). When intrarenal tissue PO2 decreases, any compensatory increase in oxygen supply via increased renal blood flow is likely to increase glomerular filtration rate. READ MORE

  4. 2. Prediction Models and Pharmacogenomics in Adult Growth Hormone Deficiency

    Author : Edna J L Barbosa; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; growth hormone deficiency; hypopituitarism; growth hormone replacement therapy; prediction models; candidate gene approach; polymorphisms; body composition; growth hormone receptor; lipid metabolism; extracellular water; pharmacogenomics;

    Abstract : The overall aim of this thesis was to study clinical and genetic factors that influence response to growth hormone replacement therapy (GHRT) in GH deficient (GHD) adults. The patients were part of a cohort of adults with hypopituitarism and severe GHD who were studied before and after 12 months of GHRT. READ MORE

  5. 3. Clinical and genetical studies in cystic fibrosis and pseudohypoaldosteronism

    Author : Charlotta Schaedel; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pseudohypoaldosteronism type 1; cystic fibrosis transmembrane conductance regulator CFTR ; Cystic fibrosis; pulmonary disorder; Pediatrics; epithelial sodium channel ENaC; Pediatri;

    Abstract : Cystic fibrosis (CF) is the most common severe autosomal recessive disorder among Caucasians and is caused by mutations of the chloride channel, CFTR (cystic fibrosis transmembrane conductance regulator) gene. Despite a markedly improved median survival many CF patients still die at a young age. READ MORE

  6. 4. Effect of growth and development on tissue vulnerability : a study on the perinatal rat kidney

    Author : Eva Serlachius; Karolinska Institutet; Karolinska Institutet; []
    Keywords : apoptosis; development; DNA synthesis; growth; kidney; ontogeny; PKC; proximal tubular cells; pyelonephritis; rat; sodium; sodium deficiency;

    Abstract : The infant is more vulnerable than older children and adults to pathological processes, such as metabolic disturbances and kidney infection. We have speculated that the vulnerability of the infant kidney may be related to the fact that the kidney at this time is undergoing rapid growth and development. READ MORE

  7. 5. Functional Aspects of the Juxtaglomerular Apparatus : Control of Glomerular Filtration and Renin Release

    Author : Johan Sällström; Erik Persson; Peter Hansell; Jürgen Schnermann; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : The juxtaglomerular apparatus (JGA) is a control unit of the kidney, that regulates glomerular filtration rate (GFR) and renin release, and hence extracellular volume and blood pressure. The tubuloglomerular feedback (TGF) mechanism is a negative feedback loop that regulates GFR. READ MORE