Search for dissertations about: "solid-phase synthesis"
Showing result 16 - 20 of 82 swedish dissertations containing the words solid-phase synthesis.
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16. Studies in solid phase peptide synthesis and self-assembly of cyclic peptides
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17. Improved solid phase synthesis of apamin, the principal neurotoxin of bee venom : structure-function studies based on synthetic analogues
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18. Applications of multi-component condensations and development of polyamine synthesis on solid-phase
Abstract : Solid-phase synthesis of small non-polymeric molecules has become increasingly important as a tool in the development of pharmacologically active compounds. Of particular interest are the syntheses of compounds with low molecular weight, low polarity and a reduced flexibility of the functional groups, i.e. READ MORE
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19. Studies aimed at improving the H-phosphonate approach for solid phase oligonucleotide synthesis
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20. Design and Synthesis of Potential Aminoacyl-tRNA Synthetase Inhibitors
Abstract : Aminoacyl-tRNA synthetases (aaRSs) are essential enzymes present in all living organisms, their catalytic activity is involved in the translation of the genetic code into functional proteins and they are potential targets for anti-infective agents. The first step in the biosynthetic pathway catalysed by aaRSs consists of activation of the corresponding amino acid by the reaction with ATP to form an aminoacyl-adenylate (aa-AMP), the key intermediate in the biosynthesis of proteins. READ MORE