Search for dissertations about: "solubility prediction"

Showing result 11 - 15 of 25 swedish dissertations containing the words solubility prediction.

  2. 11. In vitro-solubility and supersaturation behavior of supersaturating drug delivery systems

    Author : Amani AlHayali; Sitaram P. Velaga; Sandra Klein; Luleå tekniska universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Health Science; Hälsovetenskap;

    Abstract : The development of new pharmaceutical products has been challenged by the growing number of poorly water-soluble drugs, which often lead to suboptimal bioavailability. Various approaches, such as the use of amor-phous solid dispersions and cocrystals, have been used to improve the solu-bility, and subsequent bioavailability, of these drug molecules. READ MORE

  4. 12. Solubility of hydrogen in slags and its impact on ladle refining

    Author : Jenny Brandberg; Du Sichen; Mia Almcrantz; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Other materials science; Övrig teknisk materialvetenskap;

    Abstract : The aim of the present work was to clarify the mechanisms of hydrogen removal during vacuum degassing. The main reason for this was because the primary source of hydrogen pick-up in steel-making is the moisture in the furnace atmosphere and the raw material charged into the ladle furnace. READ MORE

  5. 13. Modelling and prediction of drug transport processes with experimental and calculated molecular properties : A multivariate approach

    Author : Thomas Österberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; farmaceutisk farmakologi; Pharmaceutical Pharmacology;

    Abstract : Less than 2% of the lead compounds generated by the pharmaceutical industry enter the exploratory drug-development phase, from which point they stand only a 10% chance of becoming a commercial medicine. A large proportion of the compounds fail due to poor biopharmaceutical properties, such as permeability and solubility. READ MORE

  6. 14. Comparison of experimentally and theoretically determined oxidation and photochemical transformation rates of some organohalogens to promote prediction of persistence

    Author : Patricia Moreira Bastos; Åke Bergman; Leif Kronberg; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oxidation; Persistence; Photolysis; QSPR; BFRs; PBDEs; OH-PBDEs; Chemistry; Kemi; miljökemi; Environmental Chemistry;

    Abstract : The diversity of choices we have to make everyday influence our environment and ourselves in more ways than most of us realise. Anthropogenic substances, such as flame retardants, date back as early as 450 BC when the Egyptians used alum to reduce flammability. READ MORE

  7. 15. New insights into solubility control mechanisms and the role of particle- and colloid-facilitated transport of metals in contaminated soils

    Author : Åsa Löv; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Particle- and colloid-mediated transport of metals can be an important leaching pathway in contaminated soils, making it necessary to include this process in risk assessments of contaminant transport. In this thesis, mechanisms involved in transport of particulate, colloidal and truly dissolved lead, chromium, zinc, arsenic and antimony were studied in an irrigation experiment performed on intact soil columns from four historically contaminated soils. READ MORE