Search for dissertations about: "solubility prediction"

Showing result 16 - 20 of 25 swedish dissertations containing the words solubility prediction.

  2. 16. Probing the prospects for structural genomics : expression and characterization of human disease-related proteins in E. coli

    Author : Niklas Hellgren; Torleif Härd; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Biokemi; Biochemistry; Biokemi;

    Abstract : Today a lot of research is directed towards the development of methods to make protein structure determination faster and more generalised. Automated, general methods for protein expression and purification, robotics for crystallisation and automatic methods for data collection will take structural biology into a new era, that of structural genomics. READ MORE

  4. 17. Alloy Design and Optimization of Mechanical Properties of High-Entropy Alloys

    Author : Saad Ahmed Sheikh; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ductility; topologically closed-pack TCP and geometrically closed-pack GCP phase; alloy design; mechanical properties; High-entropy alloys; refractory high-entropy alloys; valence electron concentration;

    Abstract : High-entropy alloys (HEAs) are described as alloys containing multi-principal elements in equal or close to equal atomic percentage. HEAs are considered as potential structural materials for high-temperature applications; where alloy design and optimization of mechanical properties is extremely critical. READ MORE

  5. 18. Development of Methods for Assessing Unbound Drug Exposure in the Brain : In vivo, in vitro and in silico

    Author : Markus Fridén; Margareta Hammarlund-Udenaes; Ulf Bredberg; Yuichi Sugiyama; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood-brain barrier; Drug transport; Tissue distribution; Transporters; Pharmacokinetics; Other pharmacy; Övrig farmaci; Biopharmacy; Biofarmaci; Pharmaceutical pharmacology; Farmaceutisk farmakologi; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Abstract : The blood-brain barrier is formed by tightly joined capillary cells with transporter proteins and acts as to regulate the brain concentration of nutrients as well as many drugs. When developing central nervous system drugs it is necessary to measure the unbound drug concentration in the brain, i.e. the unbound brain exposure. READ MORE

  6. 19. Modeling ionic liquids with ePC-SAFT ─ properties and gas solubilities

    Author : Yunhao Sun; Xiaoyan Ji; Xiaodong Liang; Luleå tekniska universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Energiteknik; Energy Engineering;

    Abstract : Global warming is now widely recognized as being the biggest global issue facing human beings. Mitigating CO2 emission from fossil-fueled power plants as well as from transports has become an urgent and worldwide research topic, in which CO2 separation is often needed. READ MORE

  7. 20. Molecular Thermodynamic Models for Nano-Micro Fluid/Solid Interfaces

    Author : Nanhua Wu; Xiaoyan Ji; Yuanhui Ji; Luleå tekniska universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Energiteknik; Energy Engineering;

    Abstract : Introducing materials with large interfaces to enhance process performance has become a feature of advanced chemical engineering, where the research focus has been changed from the traditional ideal isotropic fluid in the bulk phase to the highly non-ideal anisotropic confined fluid on the nano-micro interfaces, owing to the strong and asymmetric interactions between the complex fluids (supported metal nanoparticles, ionic liquids, proteins, etc.) and the sophisticated solid-surface (roughness, electrostatic effects, chemical heterogeneities, etc. READ MORE