Search for dissertations about: "soluble receptor"
Showing result 1 - 5 of 254 swedish dissertations containing the words soluble receptor.
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1. Structural and Functional Studies of Gas6
Abstract : The vitamin K-dependent and ubiquitously expressed 82 kDa glycoprotein product of the growth-arrest-specific-gene 6, Gas6, shows 44% sequence identity to the anticoagulant protein, protein S. Both proteins share further the same domain organization. READ MORE
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2. Processing of TNF-receptors to soluble receptor forms in myeloid cells
Abstract : TNF (Tumor Necrosis Factor) is a pro-inflammatory cytokine which binds to two cell surface receptors, TNF-R55 and TNF-R75. The receptors undergo proteolytic cleavage and release a fragment (soluble TNF-receptors or TNF-Binding Protein), TNF-R55-BP and TNF-R75-BP. Soluble TNF-receptors are able to bind and inactivate TNF. READ MORE
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3. The Soluble Form of the Axl Receptor Tyrosine Kinase
Abstract : The present investigation focus on the receptor Axl, which is a member of the receptor tyrosine kinase family. Axl is activated by the ligand Gas6 inducing cell growth and proliferation, but also regulate inflammation and vascular homeostasis. READ MORE
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4. Electron crystallography of soluble proteins
Abstract : Protein structures at moderate to high resolution can now be readily solved using an electron microscope and image processing techniques. The averaging conditions required to overcome the low signal to noise ratio of electron microscope images are particularly well satisfied by two-dimensional crystals. READ MORE
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5. A novel principle for immunomodulator delivery with hematopoietic cells as vehicles Focus on soluble TNF-receptor gene expression, targeting to secretory lysosomes and regulated secretion
Abstract : The goal of this research is to use hematopoietic cells as vehicles for targeting transgenic immunomodulators to the inflammatory sites. The work presented was focused on the anti-inflammatory soluble TNF receptor. A transmembrane soluble TNF receptor (sTNFR1) construct was expressed in hematopoietic cell lines. READ MORE