Search for dissertations about: "solute carrier"

Showing result 11 - 15 of 18 swedish dissertations containing the words solute carrier.

  2. 11. Elucidating the molecular basis of Na+/H+ exchange

    Author : Pascal F. Meier; David Drew; Simon Newstead; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; membrane protein; secondary-active transporter; Solute Carrier Transporter; ion-exchange; sodium proton exchanger; potassium proton exchanger; protein structure; cryo-EM; regulation; biokemi; Biochemistry;

    Abstract : Solute carrier (SLC) transporters are membrane transport proteins, which catalyse the movement of nutrients, ions, and drugs across cell membranes. Here, I will present our contribution to understanding the mechanism of the sodium/proton exchangers (NHE), belonging to the SLC9 family of membrane transporters. READ MORE

  4. 12. Function, Pharmacology, Evolution and Anatomical Localization of G Protein-Coupled Receptors and Solute Carriers

    Author : Tatjana Haitina; Robert Fredriksson; Gert Flik; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; Farmakologi; Medicine; medicin;

    Abstract : The G protein-coupled receptors (GPCRs) and solute carriers (SLC) are two large families of membrane-bound proteins. The aim of this study was to characterize these two families in terms of evolution and function. READ MORE

  5. 13. Establishing the mechanistic basis of sugar transport

    Author : Abdul Aziz Qureshi; David Drew; Magnus Wolf-Watz; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; membrane transport; transport energetics; nucleotide-sugar transporters; glucose transporters; malaria; cancer; Biochemistry; biokemi;

    Abstract : Sugar is a vital molecule required for cell viability and homeostasis. Sugar is important for metabolic energy, energy storage, signaling, structure and osmolyte regulation. Transport of sugar represents an important physiological process. READ MORE

  6. 14. Mechanisms triggering the recruitment of mast cell progenitors to the lung and regulation of mast cell degranulation

    Author : Behdad Zarnegar; Jenny Hallgren; Madeleine Rådinger; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mast cells; Mast cell progenitors; Recruitment; Lung; Virus; Influenza; Innate immunity; Poly I:C; IL-33; VAAT; SLC10A4; Degranulation;

    Abstract : Mast cells stem from the bone marrow and migrate via the blood as mast cell progenitors. Upon arrival in peripheral tissues, they develop into mast cells. These rare immune cells have numerous granules that contain large amounts of pro-inflammatory mediators. READ MORE

  7. 15. Effects of insulin on the decidualization of human endometrial stromal cells : in vitro studies

    Author : Ivika Jakson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Hyperinsulinemia is a known characteristic of obesity and polycystic ovary syndrome, two common clinical conditions associated with reproductive problems. However, the underlying mechanisms to reduced fertility are not fully elucidated, and the role of insulin in reproduction needs further investigation. READ MORE