Search for dissertations about: "solute carriers"
Showing result 1 - 5 of 16 swedish dissertations containing the words solute carriers.
-
1. Solute Carriers in Metabolism : Regulation of known and putative solute carriers in the central nervous system
Abstract : Solute carriers (SLCs) are membrane-bound transporter proteins, important for nutrient, ion, drug and metabolite transport across membranes. A quarter of the human genome codes for membrane-bound proteins, and SLCs make up the largest group of transporter proteins. READ MORE
-
2. Atypical Solute Carriers : Identification, evolutionary conservation, structure and histology of novel membrane-bound transporters
Abstract : Solute carriers (SLCs) constitute the largest family of membrane-bound transporter proteins in humans, and they convey transport of nutrients, ions, drugs and waste over cellular membranes via facilitative diffusion, co-transport or exchange. Several SLCs are associated with diseases and their location in membranes and specific substrate transport makes them excellent as drug targets. READ MORE
-
3. Characterization of Novel Solute Carriers in Humans, Mice and Flies : Solute Carriers in a Broad and Narrow Perspective
Abstract : The solute carrier family is the largest family of membrane-bound transporters in humans, with 430 members divided into 65 subfamilies. They transport various substrates across lipid barriers and are vital for absorption, distribution, metabolism and excretion in all cell types in the body. READ MORE
-
4. Characterization of Centrally Expressed Solute Carriers : Histological and Functional Studies with Transgenic Mice
Abstract : The Solute Carrier (SLC) superfamily is the largest group of membrane-bound transporters, currently with 456 transporters in 52 families. Much remains unknown about the tissue distribution and function of many of these transporters. READ MORE
-
5. Characterization of Amino Acid Transporters : Transporters expressed in the central nervous system belonging to the Solute Carrier family SLC38
Abstract : In cells and organelles transporters are responsible for translocation of amino acids, sugars and nucleotides among others. In the central nervous system (CNS), amino acid transporters can function as neurotransmitter transporters and nutrient sensors. READ MORE