Search for dissertations about: "sotalol"

Showing result 1 - 5 of 7 swedish dissertations containing the word sotalol.

2. 1. Risks and risk monitoring in sotalol therapy for atrial fibrillation

   Author : Hanna Lenhoff; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Background: Atrial fibrillation (AF) stands as the most prevalent arrhythmia, significantly impacting both the prognosis and symptomatology of affected individuals. Healthcare expenditures associated with AF treatment and its related complications, in terms of morbidity and mortality, are substantial. READ MORE

4. 2. Teratogenicity as a consequence of drug-induced embryonic cardiac arrhythmia : Common mechanism for almokalant, sotalol, cisapride, and phenytoin via inhibition of IKr

   Author : Anna-Carin Sköld; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; IKr; delayed rectifying K channel; embryonic cardiac arrhythmia; teratogenicity; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Toxicology; toxikologi;

   Abstract : During the last years, drugs that prolong the repolarisation phase of the myocardial action potential, due to inhibition of the rapid component of the delayed-rectifying potassium channel (IKr) have been in focus. In addition to arrhythmogenic potential, selective Ikr-blockers have also been shown to be embryotoxic and teratogenic in animal studies. READ MORE

5. 3. Atrial fibrillation : clinical presentation and management, with special emphasis on magnesium therapy

   Author : Mats Frick; Karolinska Institutet; Karolinska Institutet; []
   Keywords : atrial fibrillation; magnesium; arrhythmias; cardioversion; sotalol;

   Abstract : Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, causing disabling symptoms, risk of thromboembolic events and increased mortality. Some patients with AF are asymptomatic, but to what extent these patients differ from patients with symptoms is unclear. READ MORE

6. 4. Atrial fibrillation : clinical presentation and prevention of recurrences

   Author : Anna Nergårdh; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Atrial fibrillation; arrhythmias; beta-blocker; cardioversion; symptoms;

   Abstract : Atrial fibrillation (AF) is the most common sustained arrhythmia of clinical importance. AF is known to decrease quality of life and it is related to an increased morbidity and a risk of tromboembolic events. AF may also be asymptomatic, and to what extent patients actually are able to distinguish between sinus rhythm (SR) and AF is unknown. READ MORE

7. 5. Molecular pharmacology of amiodarone

   Author : Viktor Drvota; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Amiodarone; thyroid hormone receptors; B-adrenergic receptors; AT-1 cardiomyocytes; Western blot; solution hybridization; Fura-2; Langendorff heart; mouse; guinea pig;

   Abstract : Amiodarone (Am) is a potent class III antiarrhythmic drug. Its use is limited due to serious side effects and it was therefore used only when other therapeutic interventions proved to be ineffective. READ MORE