Search for dissertations about: "spatial data analysis"

Showing result 1 - 5 of 614 swedish dissertations containing the words spatial data analysis.

2. 1. Computational methods for analysis of spatial transcriptomics data : An exploration of the spatial gene expression landscape

   Author : Alma Andersson; Joakim Lundeberg; Omer Bayraktar; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; spatial transcriptomics; machine learning; data analysis; RNA-seq; probabilistic; statistical; models; Biotechnology; Bioteknologi;

   Abstract : Transcriptomics techniques, whether in the form of bulk, single cell/nuclei, or spatial methods have fueled a substantial expansion of our knowledge about the biological systems within and around us. In addition, the rate of innovation has accelerated over the last decade, resulting in a multitude of technological advances and new methods for generation of transcriptomics data. READ MORE

4. 2. Computational Methods for Image-Based Spatial Transcriptomics

   Author : Axel Andersson; Carolina Wählby; Anna Klemm; Filip Malmberg; Karl Åström; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Spatial omics; Spatial transcriptomics; Spatial biology; In Situ Sequencing; Visualization; Spatial statistics; Fluorescence microscopy; Computerized Image Processing; Datoriserad bildbehandling;

   Abstract : Why does cancer develop, spread, grow, and lead to mortality? To answer these questions, one must study the fundamental building blocks of all living organisms — cells. Like a well-calibrated manufacturing unit, cells follow precise instructions by gene expression to initiate the synthesis of proteins, the workforces that drive all living biochemical processes. READ MORE

5. 3. Parallel Data Streaming Analytics in the Context of Internet of Things

   Author : Hannaneh Najdataei; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; clustering; stream continuous data processing; edge computing; Internet of Things; parallelism; elasticity; data analysis; fog computing; scalability;

   Abstract : We are living in an increasingly connected world, where the ubiquitously sensing technologies enable inter-connection of physical objects, as part of Internet of Things (IoT), and provide continuous massive amount of data. As this growth soars, benefits and challenges come together, which requires development of right tools in order to extract valuable information from data. READ MORE

6. 4. Spatial analysis and modeling of nerve fiber patterns

   Author : Claes Andersson; Göteborgs universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; hierarchical models; Bayesian estimation; epidermal nerve fibers; cluster processes; spatial point processes; diabetic neuropathy; Bayesian field theory; Diabetic neuropathies; Multilevel models Statistics ; Institutionen för matematiska vetenskaper. Tillämpad matematik och statistik.; CTH;

   Abstract : Diabetic neuropathy is a condition associated with diabetes affecting the epidermal nerve fibers (ENFs). This thesis presents analysis methods and models for ENF data, with two main puroposes: to find early signs of diabetic neuropathy and to characterize how this condition changes the nerve fiber structure. READ MORE

7. 5. Spatial transcriptome and epigenome analysis with focus on prostate cancer

   Author : Maja Marklund; Joakim Lundeberg; Patrik Ståhl; Marc Friedländer; KTH; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Spatial; Spatial Transcriptomics; Spatial ATAC; epigenomics; Biotechnology; Bioteknologi;

   Abstract : Each cancer is unique, and therefore the use of general treatments are often suboptimal. If we can understand the mechanisms of cancer development, we might be able to develop effective treatments tailored to each patient. Our bodies are complex three-dimensional structures and how things are organized correlate with proper functioning. READ MORE