Search for dissertations about: "spatial understanding"

Showing result 1 - 5 of 796 swedish dissertations containing the words spatial understanding.

  2. 1. Functional understanding of space : Representing spatial knowledge using concepts grounded in an agent's purpose

    Author : Kristoffer Sjöö; Patric Jensfelt; David Vernon; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; spatial representation; autonomous robots; spatial understanding; semantic mapping; spatial relations; visual search; robot search;

    Abstract : This thesis examines the role of function in representations of space by robots - that is, dealing directly and explicitly with those aspects of space and objects in space that serve some purpose for the robot. It is suggested that taking function into account helps increase the generality and robustness of solutions in an unpredictable and complex world, and the suggestion is affirmed by several instantiations of functionally conceived spatial models. READ MORE

  4. 2. Computational Methods for Image-Based Spatial Transcriptomics

    Author : Axel Andersson; Carolina Wählby; Anna Klemm; Filip Malmberg; Karl Åström; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Spatial omics; Spatial transcriptomics; Spatial biology; In Situ Sequencing; Visualization; Spatial statistics; Fluorescence microscopy; Computerized Image Processing; Datoriserad bildbehandling;

    Abstract : Why does cancer develop, spread, grow, and lead to mortality? To answer these questions, one must study the fundamental building blocks of all living organisms — cells. Like a well-calibrated manufacturing unit, cells follow precise instructions by gene expression to initiate the synthesis of proteins, the workforces that drive all living biochemical processes. READ MORE

  5. 3. Spatial transcriptome and epigenome analysis with focus on prostate cancer

    Author : Maja Marklund; Joakim Lundeberg; Patrik Ståhl; Marc Friedländer; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Spatial; Spatial Transcriptomics; Spatial ATAC; epigenomics; Biotechnology; Bioteknologi;

    Abstract : Each cancer is unique, and therefore the use of general treatments are often suboptimal. If we can understand the mechanisms of cancer development, we might be able to develop effective treatments tailored to each patient. Our bodies are complex three-dimensional structures and how things are organized correlate with proper functioning. READ MORE

  6. 4. Engendering Spatial Planning : A Gender Perspective on Municipal Climate Change Response

    Author : Christian Dymén; Göran Cars; Richard Langlais; Susan Buckingham; KTH; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Spatial planning; climate change; gender perspective; Planering och beslutsanalys; Planning and Decision Analysis;

    Abstract : While climate change mitigation has been on the agenda of spatial planning practitioners for over two decades, adaptation has only become influential in spatial planning practice in recent years. This trend is evident not only at the municipal levelbut also at the regional and national levels. READ MORE

  7. 5. Exploring Biological Systems using Spatial Transcriptomic Technologies

    Author : Kim Thrane; Joakim Lundeberg; Patrik Ståhl; Ulf Gyllensten; KTH; []
    Keywords : Spatial Transcriptomics; single-cell RNA-seq; scRNA-seq; spatial VDJ; Spatial Isoform Transcriptomics; Biotechnology; Bioteknologi;

    Abstract : The transcriptome and the cells’ spatial organization are important determinants for the functions of biological systems, such as a tumor, brain, or skin tissue. Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful tool for profiling the transcriptome of individual cells. READ MORE