Search for dissertations about: "specificity"

Showing result 1 - 5 of 1254 swedish dissertations containing the word specificity.

  1. 1. Haematopoietic Serine Proteases A Cleavage Specificity Analysis

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Michael Thorpe; Uppsala universitet.; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mast cell; cleavage specificity; phage display; chymase; serine protease; granzyme; fish protease;

    Abstract : Mast cells are innate immune cells, historically involved in allergy responses involving IgE. Through this, they have earned a reputation as a fairly detrimental cell type. Their beneficial roles remain somewhat enigmatic although they clearly have the ability to modulate the immune system. READ MORE

  2. 2. PARN – The Tail End Function and mechanisms of specificity and processivity

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Mikael Nissbeck; Uppsala universitet.; [2019]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Poly A specific ribonuclease; Adenosine; Specificity; Processivty; Telomere biology disorders; Molekylär cellbiologi; Molecular Cellbiology;

    Abstract : Poly(A)-specific ribonuclease (PARN) is an exoribonuclease that is processive, poly(A) specific and cap-binding. PARN deadenylates the poly(A) tails present on a subset of mRNAs and non-coding RNAs, including among others certain snoRNAs, miRNAs and precursor rRNAs. READ MORE

  3. 3. Characterization of antibody specificity using peptide array technologies

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Björn Forsström; KTH.; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Antibody; Epitope mapping; Peptide array; Suspension bead array; Antigen; Specificity; Cross-reactivity; Immunization; Immunogenicity; Biotechnology; Bioteknologi;

    Abstract : Antibodies play an important role in the natural immune response to invading pathogens. The strong and specific binding to their antigens also make them indispensable tools for research, diagnostics and therapy. READ MORE

  4. 4. Substrate specificity of protein kinases studied with synthetic peptides

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Reet Toomik; Uppsala universitet.; [1997]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical sciences; protein kinase A; protein kinase C; substrate; peptide; specificity; stereospecificity; assay; SPOTS peptides; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medical and Physiological Chemistry; medicinsk och fysiologisk kemi;

    Abstract : This thesis concentrates on the substrate specificities of protein kinases A and C (PKA, PKC). Synthetic peptides are used for that purpose, both in soluble and cellulose membrane-bound form. The, stereospecificity of both protein kinases was studied with D-amino acid containing synthetic peptides. READ MORE

  5. 5. Cleavage Specificity of Mast Cell Chymases

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Mattias K. Andersson; Uppsala universitet.; [2008]
    Keywords : Biology; Immunology; Mast cell; Serine protease; Chymase; Cleavage specificity; Phage display; Biologi;

    Abstract : Mast cells (MC) are potent inflammatory cells that are known primarily for their prominent role in IgE mediated allergies. However, they also provide beneficial functions to the host, e.g. in bacterial and parasitic defence. READ MORE