Search for dissertations about: "sphingosine-1-phosphate"

Showing result 1 - 5 of 12 swedish dissertations containing the word sphingosine-1-phosphate.

  2. 1. The significance of blood vessels in organogenesis and cadherins in exploratory behaviour

    Author : Josefina Edsbagge; Göteborgs universitet; []
    Keywords : pancreas; sphingosine-1-phosphate; endothelium; epithelial-to-mesenchymal interactions; ; Cre loxP-system; cadherins; rearing;

    Abstract : Organogenesis of epithelial organs requires interaction between epithelial andmesenchymal tissues. In pancreas development three different mesenchymal derivedstructures, the notochord, the endothelial cells and the splanchnic mesenchyme inducespecification, growth and further differentiation of the pancreatic epithelium. READ MORE

  4. 2. Palmitate-induced Apoptosis in Insulin-producing β-cells

    Author : Kristofer Thörn; Peter Bergsten; Claes Wollheim; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ER stress; apoptosis; palmitate; sphingosine-1-phosphate; ceramide; beta-cell; fatty acid; Medical cell biology; Medicinsk cellbiologi; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : Type 2 diabetes is a disease characterized by the inability of pancreatic β-cells to secrete sufficient amounts of insulin to maintain normoglycemia. Increased levels of saturated fatty acids such as palmitate are believed to contribute to β-cell failure and the development of the disease. READ MORE

  5. 3. Intestinal immune cells in health and disease. Dissecting histological characteristics of inflammatory bowel disease and inflamed lung using quantitative immunohistochemical image analysis

    Author : Manar Alyamani; Adaptivt immunförsvar; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IBD; CD; UC; Quantitative imaging; COVID -19; NPP7 Nucleotide phosphodiesterase pyrophosphatase 7; alkaline sphingomyelinase; histopathology; Multiplexed IHC; Immunohistochemical staining; S1P Sphingosine-1-phosphate;

    Abstract : .... READ MORE

  6. 4. The role of N-cadherin and S1P/S1P1 in pancreas development

    Author : Jenny Johansson; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Organogenesis of epithelial organs requires interaction between epithelial and mesenchymal tissues. During pancreas development, mesenchyme-derived structures induce specification, growth and differentiation of pancreatic epithelial cells. READ MORE

  7. 5. Mechanisms of platelet-mediated fibroblast proliferation

    Author : Cecilia Berg; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Wound healing is a multicomponent event that involves a network of molecular and cellular crosstalk between cells, including leukocytes, platelets and fibroblasts. Despite increased knowledge over the past decades regarding the regulation of cell and tissue growth, the inter- and intracellular systems that control wound healing are incompletely understood. READ MORE