Search for dissertations about: "spinal cord stimulation"

Showing result 11 - 15 of 83 swedish dissertations containing the words spinal cord stimulation.

2. 11. Spinal cord grafts : interaction with cografts and effects of trophic factors

   Author : Katarzyna Trok; Karolinska Institutet; Karolinska Institutet; []
   Keywords : cord injury; spinal cord transplants; regeneration; GDNF; neurotrophins; CNTF; 5HT; immunohistochemistryKatarzyna Trok; 1996ISBN 91-6;

   Abstract : Spinal cord injury is common in the modern society, often afflicts young individuals, and often has devastating consequences. The present work studies possibilities to obtain better conditions for regeneration of the transected spinal cord in rats, conditions under which spinal cord grafts are able to establish structural and functional connections with "natural" targets, and effects of a series of neurotrophic factors on spinal cord graft survival and growth. READ MORE

4. 12. Drug-enhanced spinal cord stimulation for neuropathic pain : studies on neurochemical mechanisms and clinical applications

   Author : Gastón Schechtmann; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Acetylcholine; baclofen; cholinergic analgesia; clonidine; gabapentin; neuropathic pain; nerve injury; pregabalin; spinal cord stimulation; intrathecal drug;

   Abstract : Spinal cord stimulation (SCS) is an effective surgical treatment for neuropathic pain refractory to pharmacological therapy. For many patients suffering from this type of chronic pain, SCS is in fact the ultimate treatment option. READ MORE

5. 13. Spinal cord stimulation in chronic pain : a study of health outcomes and costs

   Author : Emma Söreskog; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Background: The aetiology of chronic pain is complex and encompasses many different causes. Chronic pain commonly arises due to spinal disorders causing pain in the back and legs. READ MORE

6. 14. Neurotransmission in CNS regions involved in pain modulation : neurochemical effects of analgesic drugs and spinal cord stimulation in the spinal cord and midbrain periaqueductal grey of the rat

   Author : Carl-Olav Stiller; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Adenosine; dorsal horn; GABA; microdialysis; neurotensin; opioids; periaqueductal gray; sciatic nerve lesion; receptor binding; spinal cord stimulation; substance P.;

   Abstract : The dorsal hom of the spinal cord and the midbrain penaqueductal grey matter (PAG) are important regions for pain modulation. In this thesis the effects of opioids and spinal cord stimulation (SCS) on the release of gamma-amino butyric acid (GABA), substance P (SP) and neurotensin (NT) were investigated in these regions of the rat by in vivo microdialysis. READ MORE

7. 15. Somatosensory Circuits in the Central Nervous System

   Author : Hannah M. Weman; Malin C. Lagerström; Sarah E. Ross; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glycine receptor alpha 3; urocortin 3; vesicular monoaminergic transporter 2; nociception; pruriception; spinal cord; somatosensory cortex; DREADD; rabies tracing; transcriptomics; Neuroscience; Neurovetenskap;

   Abstract : Spinal glycinergic neurons prevent spontaneous sensations of pain and itch, and development of persistent pain and itch conditions. The glycine receptor alpha 3 subunit (GLRA3) is suggested to be involved in certain inflammatory models, but not in acute nociception. READ MORE