Search for dissertations about: "spontaneous reporting"

Showing result 1 - 5 of 12 swedish dissertations containing the words spontaneous reporting.

2. 1. Spontaneous reporting of adverse drug reactions : Possibilities and limitations

   Author : Martin Bäckström; Tom Mjörndal; Rune Dahlqvist; Folke Sjökvist; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; adverse drug reactions; spontaneous reporting; metamizole; general practitioners; hospital physicians; under-reporting; economical inducement; nurses.; Farmakologi; Pharmacological research; Farmakologisk forskning; Clinical Pharmacology; klinisk farmakologi;

   Abstract : Adverse drug reactions (ADRs) constitute a major problem in society and in drug therapy. They are a common cause of short-term hospitalization, prolonged hospitalization and death. Spontaneous reporting of ADRs remains one the most effective methods for detecting new and serious drug reactions. READ MORE

4. 2. Pharmacovigilance : spontaneous reporting in health care

   Author : Elisabet Ekman; Göran Petersson; Susanna Wallerstedt; Linnéuniversitetet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacovigilance; adverse drug reaction; spontaneous reporting; nurses; physicians; attitudes; torsades de pointes; erectile dysfunction; Biomedical Sciences; Biomedicinsk vetenskap;

   Abstract : Pharmacovigilance in healthcare is essential for safe drug treatment. Spontaneous reporting is the most common source of information in the context of implementing label changes and taking a drug off the market. However, underreporting is found to be very prevalent. READ MORE

5. 3. The use of Bayesian confidence propagation neural network in pharmacovigilance

   Author : Andrew Bate; Umeå universitet; []
   Keywords : adverse drug reactions; pharmacovigilance; signal detection; spontaneous reporting; data mining; Bayesian statistics; BCPNN; neural network; medicinsk farmakologi; Medical Pharmacology;

   Abstract : The WHO database contains more than 2.8 million case reports of suspected adverse drug reactions reported from 70 countries worldwide since 1968. The Uppsala Monitoring Centre maintains and analyses this database for new signals on behalf of the WHO Programme for International Drug Monitoring. READ MORE

6. 4. Spontaneous abortion : risk factors and measurement of exposures

   Author : Lena George; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Case-control study; caffeine; cotinine; environmental tobacco smoke; epidemiology; fetal karyotype; folate; maternal smoking; pregnancy; repeated spontaneous abortion; risk assessment; smoking cessation; spontaneous abortion; validation study;

   Abstract : The overall objectives of this thesis were to increase the understanding of the etiology of spontaneous abortion and repeated spontaneous abortion, and to evaluate possibilities of exposure assessment during pregnancy. Data from a Swedish population-based case-control study of spontaneous abortion, performed in Uppsala County 1996-98, formed the base for the three first studies of the thesis. READ MORE

7. 5. Hazards of Drug Therapy : On the Management of Adverse Drug Reactions: From Signal Detection and Evaluation to Risk Minimization

   Author : Karin Hedenmalm; Marja-Liisa Dahl; Gunnar Alvan; Ellen Vinge; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; adverse drug reactions; spontaneous reporting systems; drug regulation; pharmacovigilance; incidence; Farmakologi; Pharmacological research; Farmakologisk forskning;

   Abstract : Spontaneous reporting systems (SRSs) for adverse drug reactions (ADRs) have been developed as a result of the thalidomide disaster, whereby thousands of children world-wide were born with birth defects. The Swedish Adverse Drug Reactions Advisory Committee was established in 1965. READ MORE