Search for dissertations about: "st2"

Showing result 1 - 5 of 14 swedish dissertations containing the word st2.

  2. 1. Novel Biomarkes in Acute Respiratory Failure and Chronic Obstructive Pulmonary Disease

    Author : Brynja Jónsdóttir; Kardiovaskulär forskning - hypertoni; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chronic obstructive pulmonary disease; Dyspnea; Respiratory failure; Biomarkers; GDF-15; ST2; IL-8; noninvasive ventilation; Acute Respiratory Failure; Chronic obstructive pulmonary disease; Dyspnea; Biomarkers; ST2; IL-8; GDF-15; Prognosis and survival; Hypercapnia;

    Abstract : Abstract Background: Dyspnea is a common manifestation of a range of conditions and diseases, sometimes with multiple contributing factors. A subgroup of these patients present with acute hypecapnic respiratory failure (AHRF) and are treated with non-invasive positive pressure ventilation (NPPV). READ MORE

  4. 2. Targeting the IL-33/ST2 pathway in asthma : implications for development, exacerbation and treatment

    Author : Anna Zoltowska Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Asthma is a term that encompasses a disease spectrum with different phenotypes that vary in severity and whose common characteristic is airflow limitation. Allergic asthma is the most common phenotype of asthma and is characterized by allergen induced inflammatory responses, airway hyperresponsiveness (AHR), and remodeling. READ MORE

  5. 3. Eosinophils, their progenitors and T helper cells in allergic airway inflammation

    Author : You Lu; Göteborgs universitet; []
    Keywords : eosinophils; eosinophil progenitors; T helper cells; Th2 cells; IL-33; migration; Asthma;

    Abstract : Introduction: Asthma is a heterogeneous chronic lung disease associated with pronounced inflammatory changes in the airways. Eosinophilic inflammation is the trait that is best linked to symptoms and treatment responses in allergic asthma. READ MORE

  6. 4. Mechanisms triggering the recruitment of mast cell progenitors to the lung and regulation of mast cell degranulation

    Author : Behdad Zarnegar; Jenny Hallgren; Madeleine Rådinger; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mast cells; Mast cell progenitors; Recruitment; Lung; Virus; Influenza; Innate immunity; Poly I:C; IL-33; VAAT; SLC10A4; Degranulation;

    Abstract : Mast cells stem from the bone marrow and migrate via the blood as mast cell progenitors. Upon arrival in peripheral tissues, they develop into mast cells. These rare immune cells have numerous granules that contain large amounts of pro-inflammatory mediators. READ MORE

  7. 5. Mechanisms of tumor microenvironment in promoting metastasis

    Author : Patrik Andersson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Tumor tissues contain diverse cell populations that relentlessly cross-communicate with each other in the tumor microenvironment. In addition to malignant cells, infiltration of other host cells including inflammatory cells, fibroblasts, and cells in the vessel walls in tumors significantly contribute to tumor growth and metastasis. READ MORE