Search for dissertations about: "startle habituation"

Found 5 swedish dissertations containing the words startle habituation.

  2. 1. Fear, Startle, and Fear-Potentiated Startle : Probing Emotion in the Human Brain

    Author : Anna Pissiota; Mats Fredrikson; Scott Rauch; Uppsala universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Psychology; anxiety; attention; brain; fear; fear-potentiated startle; human; neuroimaging; positron emission tomography; posttraumatic stress disorder; regional cerebral blood flow; startle; startle habituation; symptom provocation; Psykologi; Psychology; Psykologi; Psychology; psykologi;

    Abstract : The present thesis explored the neurobiological basis of three aspects of defense behaviors in humans. Positron emission tomography methodology was used, and changes in regional cerebral blood flow (rCBF) were measured as an index of neural activity. READ MORE

  4. 2. Cognitive function studied in animal models of schizophrenia

    Author : Erik Pålsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phencyclidine; nitric oxide; prepulse inhibition; latent; nitric oxide; prepulse inhibition; latent inhibition; habituation; NMDA receptor; rat; mouse; cognition; schizophrenia;

    Abstract : Cognitive dysfunction is considered a core deficit of schizophrenia, which currently lacks effective pharmacological treatment. In order to identify novel and more effective drug treatments, translational experimental animal models of cognitive dysfunction are required. Schizophrenia-like symptoms can be induced in humans by phencyclidine (PCP). READ MORE

  5. 3. Schizophrenia and Nitric Oxide: Deficits in Information Processing Invetigated in Animal Models

    Author : Daniel Klamer; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phencyclidine – nitric oxide – prepulse inhibition – habituation – acoustic startle – cAMP – in vivo microdialysis – NMDA receptor – rat – mouse – schizophrenia;

    Abstract : Rationale: Schizophrenia-like symptoms can be induced in humans by phencyclidine (PCP), a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor. Schizophrenic patients and PCP-treated animals display deficits in pre-attentive information processing, as assessed by e.g. prepulse inhibition of the acoustic startle response. READ MORE

  6. 4. Genetic gating of human fear, fear learning and extinction : psychophysiological, brain imaging (fMRI) and clinical studies

    Author : Tina B Lonsdorf; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Individuals differ in their reaction to the same environmental stressor. After being opposed to the same trauma, some individuals will develop affective pathologies, while others will not. This is assumed to result, at least partly, from a differential genetic vulnerability. READ MORE

  7. 5. Cognition and social behaviour in schizophrenia: An animal model investigating the potential role of nitric oxide

    Author : Caroline Wass; Göteborgs universitet; []
    Keywords : schizophrenia; cognition; memory; Morris water maze; social function; social interaction; phencyclidine; nitric oxide; L-NAME; rat;

    Abstract : Cognitive deficits are the single strongest predictor of functional outcome in patients with schizophrenia. Furthermore, these deficits are not satisfactorily alleviated by available antipsychotic treatment. READ MORE