Search for dissertations about: "statins"

Showing result 1 - 5 of 73 swedish dissertations containing the word statins.

  1. 1. Statins, HMGCR and Breast Cancer

    Author : Olöf Bjarnadottir; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Statins; HMGCR; Cyclin D1; p27; Clinical trial; Gene expressionprofiling; cholesterol-lowering medication;

    Abstract : .... READ MORE

  2. 2. Power of the Pill : Views about Cardiovascular Risk and the Risk-reducing Effect of Statins

    Author : Per Lytsy; Ragnar Westerling; Gunilla Burell; Arne Melander; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; Statins; lipid-lowering drugs; cholesterol; treatment expectations; beliefs; adherence; health behaviour; Social medicine; Socialmedicin; Community pharmacy services; Samhällsfarmaci; Family medicine; Allmänmedicin; Public health science; Folkhälsovetenskap; Community medicine; Samhällsmedicin; Social Medicine; Socialmedicin;

    Abstract : Medical treatments with statins are prescribed to patients with increased risk of cardiovascular events. The benefits from statin treatment are well documented in clinical trials, but long-term adherence in patients is low, indicating that patients have an uncertainty about the necessity and benefits of treatment. READ MORE

  3. 3. Statins, Lipids, and Mutations: Consequences for the Heart and Immune System

    Author : Emil G. Ivarsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CAAX Proteins; Statins; RHO Proteins; Dilated Cardiomyopathy;

    Abstract : CAAX proteins are a group of proteins that undergo a three-step protein maturation process that renders the proteins carboxyl-terminus hydrophobic and prone to localize to cellular membranes, where they have their primary function. The first step in this process is called prenylation, which is the covalent attachment of a lipid, either a 15-carbon farnesyl or a 20-carbon geranylgeranyl lipid, to the carboxyl-terminal cysteine residue by the enzymes farnesyltransferase (FTase) and geranylgeranyltransferase type I (GGTase-I), respectively. READ MORE

  4. 4. Pharmacoepidemiology of Antibiotics, Weak Opioids and Statins with Special Reference to Socioeconomic Aspects - an Ecological Approach

    Author : Karin Henricson; Institutionen för hälsovetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Farmakologi; toxicology; pharmacy; pharmacognosy; Pharmacological sciences; statins; weak opioids; antibiotics; effectiveness; socioeconomic factors; Ecologic studies; drug utilisation; farmakognosi; farmaci; toxikologi; Social medicine; Socialmedicin; samhällsmedicin;

    Abstract : The influence of socioeconomic factors on drug utilisation has been studied by pharmacoepidemiological analyses involving 1) drugs that are used to cure disease, such as antibiotics, 2) drugs that are used to alleviate symptoms, such as weak opioids, and 3) drugs that are used to prevent disease, such as statins. In a large Swedish city (Malmö), the utilisation of four major drug groups (ATC-groups A = alimentation, C = circulation, N = nervous system, and R = respiration) correlated positively with an unfavourable socioeconomic situation, most pronouncedly with group N and least so with group R. READ MORE

  5. 5. Statin treatment and beta-Amyloid Production in Patients with Alzheimer s Disease

    Author : Kina Höglund; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Alzheimer s disease; amyloid precursor protein; beta-amyloid; cholesterol; statins; CSF;

    Abstract : Alzheimer s disease (AD) is a progressive neurodegenerative disorder pathologically characterized by neurofibrillary tangles and amyloid plaques. According to the amyloid cascade hypothesis, the increased production of beta-amyloid (Abeta), derived form the amyloid precursor protein (APP), and its aggregation into plaques are key pathological events, driving neurodegeneration in AD. READ MORE