Search for dissertations about: "stepwise"

Showing result 1 - 5 of 294 swedish dissertations containing the word stepwise.

  2. 1. Concerted or Stepwise? : β-Elimination, Nucleophilic Substitution, Copper Catalysed Aziridination and Ruthenium Catalysed Transfer Hydrogenation Studied by Kinetic Isotope Effects and Linear Free-Energy Relationships

    Author : Per Ryberg; Heinz F. Koch; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Kinetic isotope effect; linear free energy relationship; elimination; substitution; aziridination; transfer hydrogenation; Organisk kemi; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Abstract : This thesis describes the use of kinetic isotope effects, linear free energy relationships and stereochamical studies to distinguish between different mechanistic alternatives and to obtain information about transition state structure.In the first part fluorine and deuterium kinetic isotope effects were determined for the base promoted HF elimination from 4-fluoro-4-(4’-nitrophenyl)butane-2-on. READ MORE

  4. 2. Concerted and stepwise solvolytic elimination and substitution reactions : evidence for solvent-promoted E2 reaction

    Author : Qingshui Meng; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : .... READ MORE

  5. 3. Flexural Strengthening of Reinforced Concrete Beams Using Externally Bonded CFRP--An Innovative Method for the Application of Prestressed CFRP Laminates

    Author : Jincheng Yang; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; interfacial stress; anchorage; mesh sensitivity; externally bonded; reinforced concrete; flexural strengthening; optimization; smeared length; finite element modeling; carbon fiber reinforced polymer CFRP ; stepwise prestressing; debonding;

    Abstract : A large number of existing bridges in European countries are structurally deficient and functionally obsolete due to the deterioration of aging bridges and the lack of structural and geometric capacity to accommodate the increasing traffic volume and load levels. To meet the demand for holistic and effective strengthening techniques the SUREBRIDGE solution is proposed for the refurbishment of concrete bridges, which includes the technique of using prestressed carbon fiber reinforced polymer (CFRP) laminate as externally bonded reinforcement for flexural strengthening. READ MORE

  6. 4. Covariate Model Building in Nonlinear Mixed Effects Models

    Author : Jakob Ribbing; E. Niclas Johnsson; Mats O. Karlsson; Janet Wade; Uppsala universitet; []
    Keywords : Pharmacokinetics Pharmacotherapy; Pharmacokinetics; Pharmacodynamics; Modeling; Covariate selection; Stepwise selection; Covariate analysis; Methodology; Model validation; Model evaluation; Type-2 diabetes; Beta-cell function; Meta analysis; Cross-validation; Least absolute shrinkage and selection operator; Pharmacometrics; ED optimization; Farmakokinetik Farmakoterapi;

    Abstract : Population pharmacokinetic-pharmacodynamic (PK-PD) models can be fitted using nonlinear mixed effects modelling (NONMEM). This is an efficient way of learning about drugs and diseases from data collected in clinical trials. READ MORE

  7. 5. Using life cycle assessment to support the development of electrified road vehicles. Component data models, methodology recommendations and technology advice for minimizing environmental impact

    Author : Anders Nordelöf; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; inverter; magnet; LCI; electrical machine; stepwise improvements; electric vehicle; LCA; inventory data; motor; critical review; scalable model;

    Abstract : The anthropogenic pressure on the Earth system already overshoots safe limits for climate change, so there is an urgent need to drastically reduce greenhouse gas emissions caused by transportation. Electric propulsion technology is a promising solution that can decouple fossil fuel use from road vehicle traffic. READ MORE