Search for dissertations about: "stomach tumor"

Showing result 11 - 15 of 19 swedish dissertations containing the words stomach tumor.

  1. 11. Genomic Profiling, Mutations and Deranged Signaling in Esophageal Cancer and Hereditary Colorectal Cancer

    Author : Anna Isinger Ekstrand; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Esophageal cancer; hereditary cancer; HNPCC; copy number analysis; CGH; gene expression; Wnt; PIK3CA; CHEK2; gastric cancer; colorectal cancer;

    Abstract : Esophageal cancer and colorectal cancer represents two major types of gastrointestinal tumors. Though refined surgery and introduction of novel chemotherapeutics have improved outcome, more than 2500 Swedes die from these diseases every year. Novel markers for early diagnosis, prognosis and treatment prediction are therefore needed. READ MORE

  2. 12. Engineering of alternative scaffold derived drug conjugates and fusion-toxins for targeted cancer therapy

    Author : Wen Yin; Torbjörn Gräslund; Serge Muyldermans; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; HER2; Affibody; Cancer; ADAPT; Protein engineering; PE38; DM1; MMAE; MMAF; Biotechnology; Bioteknologi;

    Abstract : Cancer is a major health problem, with premature death for many patients, and with a high monetary cost to society. The disease is complex to treat due to the many different types, but also because the disease-causing cells, that needs to be removed, are very similar to the normal cells. READ MORE

  3. 13. Epidemiological and experimental studies on sarcoma with focus on gastrointestinal stromal tumors

    Author : Fredrik Karlsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Sarcoma is the common denominator for malignant tumors of mesenchymal origin. Sarcomas encompass almost 100 diagnoses with different histology, molecular features and natural history, and may present in any part of the body. The most common sarcoma in the abdomen is the gastrointestinal stromal tumor (GIST). READ MORE

  4. 14. Asthma and cancer among pulp and paper mill workers

    Author : Eva Andersson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epidemiology; pulp and paper industry; irritant-induced asthma; gassings; cancer; sulfate mills; sulfite mills; maintenance work; brain tumors; glioma; lung cancer; asbestos;

    Abstract : There were two main aims of this thesis. One was to study if repeated high exposures to irritant gases give rise to new-onset asthma, and the other was to study if exposure in pulp and paper mills were associated with cancer. READ MORE

  5. 15. Aspects of gastroesophageal reflux and risk for esophageal cancer : an epidemiological approach

    Author : Weimin Ye; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Gastroesophageal reflux; anti-reflux surgery; esophagus; adenocarcinoma; squamous- cell carcinoma; H. pylori; gastric atrophy; DNA repair gene; polymorphism; cohort study; case-control study; relative risk;

    Abstract : Aims: The aims of this study were to confirm, in a prospective study, the link between gastroesophageal reflux. and risk of adenocarcinoma of the esophagus and gastroesophageal junction observed in retrospective studies, to investigate into the effects of anti-reflux surgery, and to shed light on some possible mechanisms behind the alleged carcinogenicity. READ MORE