Search for dissertations about: "stratum"

Showing result 16 - 20 of 47 swedish dissertations containing the word stratum.

  2. 16. Studies on the pH gradient in normal and ichthyotic human skin

    Author : Hans Öhman; Linköpings universitet; []
    Keywords : keratinization; hyperkeratosis; desquamation; filaggrin; cholesterolsulfate; tape stripping; MEDICINE; MEDICIN;

    Abstract : In search for pathogenetic mechanisms underlying hyperkeratosis, we examined the pH gradient across the stratum corneum in normal and ichthyotic skin. Twenty students and employees, (12 men and 8 womenaged 25-69 years) served as controls. Patients with ichthyoses were recruited from the outpatient clinic (13 men aged 12-71 years). READ MORE

  4. 17. Electrical impedance of human skin and tissue alterations : mathematical modeling and measurements

    Author : Ulrik Birgersson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Electrical impedance;

    Abstract : The overall aim of the studies in this thesis is twofold. One is oriented towards calibrating a classifier in differentiating between malignant melanoma and benign nevi of the skin. READ MORE

  5. 18. Molecular structure of the human skin’s barrier : elucidation, formation and utilization

    Author : Ali Narangifard; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The main focus of this study is the permeation barrier of human skin. Original cryo-electron microscopic images from near native samples of human epidermis was used as the guiding reference to assemble in silico molecular models and also to assess the possibility of their presence in the barrier. READ MORE

  6. 19. In vitro Studies of Genodermatoses Affecting Cytoskeletal Integrity and Lipid Processing in Human Epidermis : Pathogenic Mechanisms and Effects of Retinoid Therapy

    Author : Hao Li; Hans Törmä; Anders Vahlquist; Mikael Ivarsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Congenital Ichthyosiform Erythroderma; Epidermolytic Hyperkeratosis; Ceramides; Keratins; Retinoids; Molecular Probe Techniques; Transglutaminases; Lipoxygenases; Fatty Acid Transporter Proteins; Keratinocytes; Epidermis; Medicinsk vetenskap; Medical Science;

    Abstract : Autosomal dominant epidermolytic ichthyosis (EI) is a rare disease characterized by intra-epidermal blistering due to mutations in either of two keratin genes, KRT1 and KRT10, expressed by suprabasal keratinocytes. Autosomal recessive congenital ichthyosis (ARCI) is a non-blistering, hyperkeratotic disease caused by mutations in one of the following genes: ABCA12, ALOX12B, ALOXE3, TGM1, CYP4F22, NIPAL4 and SLC27A4, which are all essential for skin barrier homeostasis. READ MORE

  7. 20. Society Inhaled. Social Epidemiology of COPD

    Author : Sten Axelsson Fisk; Socialepidemiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Social Epidemiology; Social Medicine; Chronic obstructive pulmonary disease COPD ; Intersectionality; Smoking : epidemiology; Social determinants of health;

    Abstract : Chronic Obstructive Pulmonary Disease (COPD) is a common disease that in its advanced stages is a life-limiting condition and a leading cause of death globally. This thesis aims at increasing the understanding of the socioeconomic disparities that exist both for COPD and its major risk factor, tobacco smoking. READ MORE