Search for dissertations about: "streptococcal toxic shock syndrome"

Showing result 11 - 15 of 16 swedish dissertations containing the words streptococcal toxic shock syndrome.

2. 11. Immunomodulation by intravenous immunoglobulin : the effect on cytokine production studied at the single-cell level

   Author : Ulrika Skansén-Saphir; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Preparations of pooled human immunoglobulin for intravenous use (IVIg) have an established therapeutic role in immunodeficiencies, Idiopathic Thrombocytopenic Purpura and Kawasaki's disease and has been attempted in other immunologically mediated conditions including autoimmunity, malignancies, bone marrow transplantation and serious infections such as group A streptococcal toxic shock syndrome. The effects of IVIg on cytokine synthesis in peripheral blood mononuclear cells (PBMC) was studied in vitro by applying a new immunohistochemical method for detection of cytokine production at a single cell level. READ MORE

4. 12. Neutrophil interactions with Streptococcus pyogenes and Staphylococcus aureus

   Author : Julia Uhlmann; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Streptococcus pyogenes and Staphylococcus aureus are Gram-positive bacteria that share many features, including clinical presentations and pathogenic mechanisms, and yet, they still have unique properties. They both cause diseases ranging from uncomplicated infections to severe invasive diseases, such as sepsis and toxic shock syndrome, as well as severe tissue infections including necrotizing fasciitis and necrotizing pneumonia. READ MORE

5. 13. Structural Basis of Immune Receptor Binding by Staphylococcal Superantigens

   Author : Karin Rödström; Medicinsk strukturbiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Superantigen; X-ray Crystallography; T cell receptor; Major histocompatibility complex;

   Abstract : Superantigens (SAgs) are toxins capable of inducing a massive immune response, leading to severe disease. They are secreted by the bacteria Staphylococcus aureus and Streptococcus pyogenes, which produce the staphylococcal enterotoxins and streptococcal pyogenic exotoxins, respectively. READ MORE

6. 14. Superantigens in group A streptococcus : gene diversity and humoral immune response

   Author : Linda Maripuu; Mari Norgren; Susan Hollingshead; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Group A streptococcus; Streptococcus pyogenes; superantigen SAg ; SAg-gene profile; M-protein; emm-genotype; biomedicinsk laboratorievetenskap; biomedical laboratory science;

   Abstract : Group A streptococcus (GAS) is a strictly human pathogen that causes infections ranging from asymptomatic carriage to the highly lethal streptococcal toxic shock syndrome (STSS). GAS are classified according to the sequence of the variable 5’ end of the emm-gene that encodes the surface associated M-protein. READ MORE

7. 15. Innate lymphocyte responses in inflammatory diseases

   Author : Johanna Emgård; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The immune system is a highly sophisticated system that has evolved to protect the host from external and internal threats. However, under some circumstances the immune response can get dysregulated and cause inflammatory diseases. READ MORE