Search for dissertations about: "streptococcal toxic shock syndrome"

Showing result 6 - 10 of 16 swedish dissertations containing the words streptococcal toxic shock syndrome.

  2. 6. Streptococcal and staphylococcal tissue infections : therapeutic challenges and opportunities

    Author : Helena Bergsten; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Streptococcus pyogenes and Staphylococcus aureus have been leading causes of human infections throughout history. S. pyogenes is of the top-ten pathogens responsible for most death globally, 0.5 million deaths per year. READ MORE

  4. 7. Clinical and pathophysiological aspects of sepsis

    Author : Anna Linnér; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Severe sepsis and septic shock represent challenging problems for the health care system. Despite adequate antibiotics and modern intensive care, severe sepsis is associated with a substantial mortality rate of around 30%, which rises even higher if exacerbated by septic shock, and the incidence continues to increase. READ MORE

  5. 8. Actions of Antimicrobial Peptides and Bacterial Components in Inflammation

    Author : Thorgerdur Sigurdardottir; Anestesiologi och intensivvård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sepsis; LL-37; M1 protein; S. pyogenes; Toll-like receptors; phenylephrine; nitr1c oxide; antimicrobial peptides;

    Abstract : Antimicrobial peptides are evolutionally ancient parts of the innate immune system and their primary role is to protect us from infections. The human cathelicidin-derived antimicrobial peptide, LL-37, not only possesses broad spectrum antimicrobial activities but is also able to bind and neutralize bacterial lipopolysaccharide (LPS), an important trigger of the widespread inflammatory response contributing to septic shock. READ MORE

  6. 9. Receptor Interactions Between Pathogenic Bacteria and Host Cells

    Author : Lena Lövkvist; Ann-Beth Jonsson; Heiko Herwald; Uppsala universitet; []
    Keywords : Microbiology; Type IV pili; Lipooligosaccharide; ScpC protease; CD46; Mikrobiologi;

    Abstract : This thesis focuses on host and pathogen specific interactions during invasive disease. We have investigated the role and impact of different virulence factors of Neisseria gonorrhoeae, N. meningitidis and Streptococcus pyogenes on host epithelial cells and in vivo. N. READ MORE

  7. 10. Phagocytic cells and Streptococcus pyogenes in invasive infections : an inflammatory relationship

    Author : Johanna Snäll; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Severe Streptococcus pyogenes infections, such as streptococcal toxic shock syndrome and necrotizing soft tissue infections, are rare but life threatening conditions. They are characterized by high bacterial load and a hyper-inflammatory state. The aim of this thesis was to investigate interactions between S. READ MORE