Search for dissertations about: "striatum"

Showing result 1 - 5 of 227 swedish dissertations containing the word striatum.

  1. 1. Information processing in the Striatum a computational study

    University dissertation from Stockholm : KTH

    Author : Johannes Hjorth; Jeanette Hellgren Kotaleski; Anders Lansner; Kim Blackwell; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; striatum; fast spiking interneuron; gap junctions; synchronisation; up-state detection; CaMKII; mathematical modelling; MEDICINE Morphology; cell biology; pathology Cell biology Neuroscience; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi Neurovetenskap;

    Abstract : The basal ganglia form an important structure centrally placed in the brain. They receive input from motor, associative and limbic areas, and produce output mainly to the thalamus and the brain stem. The basal ganglia have been implied in cognitive and motor functions. READ MORE

  2. 2. Computer Modelling of Neuronal Interactions in the Striatum

    University dissertation from Stockholm : KTH

    Author : Johannes Hjorth; Jeanette Hellgren Kotaleski; Kevin Gurney; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; striatum; fast spiking interneurons; medium spiny projection neurons; gap junctions; interoperability; MUSIC; TECHNOLOGY Information technology Computer science; TEKNIKVETENSKAP Informationsteknik Datavetenskap;

    Abstract : Large parts of the cortex and the thalamus project into the striatum,which serves as the input stage of the basal ganglia. Information isintegrated in the striatal neural network and then passed on, via themedium spiny (MS) projection neurons, to the output stages of thebasal ganglia. READ MORE

  3. 3. Neuroprotection and neurogenesis after experimental stroke

    University dissertation from Andreas Arvidsson, Section of Restorative Neurology, Wallenberg Neuroscience Center, BMC A-11, SE-221 84, Lund

    Author : Andreas Arvidsson; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; stereology; rat; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; BrdU; immunohistochemistry; in situ hybridization; subventricular zone; striatum; dentate gyrus; neuronal replacement; neuronal survival; Focal cerebral ischemia; glial cell line-derived neurotrophic factor;

    Abstract : In this thesis, two potential endogenous mechanisms for neuronal survival and repair have been investigated in a rat model of stroke, middle cerebral artery occlusion (MCAO): signaling of the GDNF family of neurotrophic factors, and neurogenesis from endogenous progenitor cells. As determined by in situ hybridization for GDNF family ligand and receptor genes, MCAO caused widespread upregulation of both components of the functional GDNF receptor, c-Ret and GFRalpha1, indicating that GDNF may be a survival signal in stroke. READ MORE

  4. 4. Brain-derived neurotrophic factor in cerebral ischemia: a quantitative study on surviving and newly formed neurons

    University dissertation from Elin Gustafsson, SRN, WNC, BMC-A11, 221 84 Lund

    Author : Elin Gustafsson; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; brain-derived neurotrophic factor; cerebral ischemia; neuronal survival; neurogenesis; hippocampus; striatum; immunocytochemistry; stereology; neuropsykologi; Neurologi; neurophysiology; neuropsychology; neurofysiologi; Neurology;

    Abstract : This study explores the role of brain-derived neurotrophic factor (BDNF) for neuronal vulnerability and neurogenesis following cerebral ischemia in the rat. Cerebral ischemia results in selective neuronal cell loss in specific brain regions. We here demonstrate the rank order of vulnerability in two regions affected by global forebrain ischemia, i. READ MORE

  5. 5. Mechanisms controlling striatal projection neurone generation, from patterning to early differentiation

    University dissertation from Håkan Toresson, Neurobiology, WNC BMC A11, S-221 84 LUND

    Author : Håkan Toresson; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pbx; meis; sonic hedgehog; small eye; pax6; gsh2; gsh1; cerebral cortex; striatum; telencephalon; mutant; development; mouse; embryo; retinoic acid; Clinical biology; Klinisk biologi;

    Abstract : The striatum is part of the telencephalon, the most anterior part of the vertebrate brain. From when it first can be identified, telencephalic morphology is highly complex and a wide range of mechanisms has been suggested to participate in its induction, patterning and neurogenesis. READ MORE