Search for dissertations about: "stromal cells"
Showing result 6 - 10 of 215 swedish dissertations containing the words stromal cells.
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6. Repair and Reconstruction of Peripheral Nerve Injuries. Treatment with G-CSF and Stromal Vascular Fraction
Abstract : While surgery is a cornerstone in treatment of peripheral nerve injuries, it is not a comprehensive approach, and outcome is unsatisfactory, especially sensory function. The present aim was to translate recent findings about stem- and progenitor cells to improve regenerative outcome, where the cells have to be autologous, available within the same surgical procedure, and minimally manipulated. READ MORE
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7. Synergistic effects of mesenchymal stromal cells and immunotherapy in experimental brain tumors
Abstract : Glioblastoma multiforme (GBM) is the most common and aggressive form of primary brain tumor. In spite of surgical resection, combined radiation therapy and chemotherapy, the mean survival is less than 15 months following diagnosis. READ MORE
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8. Thymic Stroma and T Cell Development. Impacts of Retinoic Acid Signaling
Abstract : The development of functionally competent, self-tolerant T cells in the thymus is an essential prerequisite for the formation of adaptive immune responses against foreign pathogens. Thymic epithelial cells (TECs) form specialized stromal microenvironments in the cortex (cTEC) and medulla (mTEC) of the thymus that support all stages of T cell development, from the entry of thymocyte progenitors to the exit of mature naive T cells. READ MORE
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9. Mesenchymal stromal cells in malignant glioma - Functions and therapeutic potential
Abstract : The most common malignant brain tumor in adults is a glioma called glioblastoma multiforme (GBM). About 300 persons are diagnosed with GBM every year in Sweden. Unfortunately, it is also the most aggressive brain tumor and as of today, it is not possible to cure it. READ MORE
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10. Investigations of Proneural Glioblastoma to Identify Novel Therapeutic Targets
Abstract : Malignant glioma is a highly lethal and destructive disease with no proper cure. We have investigated some of the hallmarks of cancer in connection to glioma and found ways to disrupt these and prevent tumor growth. The work is done within the context of a glioma subtype distinguished by activation of PDGF signaling termed the proneural subtype. READ MORE