Search for dissertations about: "stromal interaction molecule"

Found 5 swedish dissertations containing the words stromal interaction molecule.

  1. 1. Exploring the interactome of EF-hand proteins

    Author : Mikael Bauer; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; EF-hand; calcium; STIM; stromal interaction molecule; secretagogin; Calmodulin; calbindin D28k; protein-protein interactions; zinc; protein array;

    Abstract : EF-hand proteins are central in many cellular processes being the main group of Ca2+-sensing and buffering proteins in the cell. In the work presented in this thesis we study ligand interactions of three EF-hand proteins; calmodulin, calbindin D28k and secretagogin. READ MORE

  2. 2. The role of estrogens and the microenvironment in lymphoma progression and drug sensitivity

    University dissertation from Stockholm : Karolinska Institutet, Dept of Biosciences and Nutrition

    Author : Jiyu Guan; Karolinska Institutet.; Karolinska Institutet.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Lymphomas are a group of cancers which originate from lymphatic cells. More than 90% of the lymphomas belong to the group of Non-Hodgkin lymphoma (NHL), which in itself is a non-homogeneous group consisting of different NHL subtypes. Traditionally, lymphomas are not thought of as hormone-related cancers. READ MORE

  3. 3. Soluble intercellular and vascular cell adhesion molecules-1 in lymphoid neoplasms : A clinical and prognostic study of Hodgkin's disease, non-Hodgkin's lymphomas and chronic B-lymphocytic leukaemia

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Ilse Christiansen; Uppsala universitet.; [1998]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Hodgkin s disease; non-Hodgkin s lymphomas; chronic lymphocytic leukaemia; sICAM-1; sVCAM-1; prognostic markers; VCAM-1; ICAM-1; Hodgkin cell lines; Onkologi; MEDICINE Surgery Oncology; MEDICIN Kirurgi Onkologi; Clinical Immunology; klinisk immunologi;

    Abstract : The interaction of soluble adhesion molecules with adhesion ligands expressed by immunological cells interfere with the cell-cell adhesion essential for the signal transductions that initiate immunological responses. Preliminary data suggest that soluble adhesion molecules also promote angiogenesis. READ MORE

  4. 4. The role of CD30 in atopic allergy

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : Åsa Bengtsson; Karolinska Institutet.; Karolinska Institutet.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CD30; sCD30; CD30L; allergy; atopic dermatitis; T-cell clone; Th1 Th2; placenta; glutathione GSH ; N-acetyl-L-cysteine NAC ;

    Abstract : The 120 kDa CD30 molecule belongs to the tumour necrosis factor (TNF) receptor superfamily and is expressed by activated lymphoid cells. Small populations of CD30+ cells have been detected in the peripheral lymphoid organs, as well as in the thymus. A subset of CD45RO+, so-called memory T cells, also express CD30 after various kind of stimuli. READ MORE

  5. 5. Regulation of cell morphology and adhesion in B lymphocytes by interleukin-4

    University dissertation from Stockholm : Karolinska Institutet, Department of Cell and Molecular Biology

    Author : Edward Davey; Karolinska Institutet.; Karolinska Institutet.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B lymphocytes; interleukin-4; lipopolysaccharide; CD40; cell adhesion; cell morphology; cytoskeleton; microvilli;

    Abstract : The different stages in lymphocyte differentiation and activation are associated with profound changes in cell morphology. Under normal development, lymphocytes are at different times in direct contact with stromal cells and extracellular matrix, they transverse endothelium, are transported via blood and lymphatic vessels, home to specific lymphoid organs and may undergo antigen-driven activation events. READ MORE