Search for dissertations about: "structural markers"

Showing result 1 - 5 of 109 swedish dissertations containing the words structural markers.

2. 1. Method Development in Quantitative and Structural Proteomics using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

   Author : Charlotte Hagman; Per Håkansson; Jonas Bergquist; Jos Buijs; Michael Przybylski; Uppsala universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; Cerebrospinal Fluid; Electrospray Ionization; Fourier Transform Ion Cyclotron Resonance Mass Spectrometry; Global Markers; High Performance Liquid Chromatography; Gas-Phase Exchange; Hydrogen Deuterium Exchange; Plasma; Protoemics; Quantification; Structural Elucidation; Bioteknik; Bioengineering; Bioteknik;

   Abstract : In this thesis, methods for studying different aspects of proteomics were developed with Fourier Transform Ion Cyclotron Resonance, (FTICR), mass spectrometry. The FTICR technique provides ultra-high mass resolving power, mass accuracy at sub ppm level and sensitivity in the attomole region. READ MORE

4. 2. microRNAs: from biogenesis to organismal tracing

   Author : Wenjing Kang; Marc Friedländer; Jens Lagergren; Ulf Ørom; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; microRNA; microRNA biogenesis; taxonomical identification; high throughput sequencing; xenomiRs; RNA structure; high throughput screening; molekylär biovetenskap; Molecular Bioscience;

   Abstract : MicroRNAs (miRNAs) are short noncoding RNAs of around 22 nucleotides in length, which help to shape the expression of most mRNAs. Perturbation of miRNA expression has revealed a variety of defects in development, cell specification, physiology and behavior. READ MORE

5. 3. Molecular and clinical studies of cartilage and bone macromolecules in arthritis

   Author : Bengt Månsson; Reumatologi och molekylär skelettbiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skeleton; Prognosis; Tissue damage; Bone markers; Cartilage markers; Rheumatoid arthritis; Psoriatic arthritis; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi;

   Abstract : The pathogenesis of inflammatory arthritides include synovial inflammation and joint tissue destruction. Tissue destruction has traditionally been regarded a consequence of inflammation, but recent observations indicate that the processes are not always closely linked and may proceed uncoupled. READ MORE

6. 4. Sveconorwegian orogenesis in the southwestern Baltic Shield - Zircon geochronology and tectonothermal setting of orthogneisses in SW Sweden

   Author : Jenny Andersson; Berggrundsgeologi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Petrology; Geologi; fysisk geografi; physical geography; Geology; structural markers; augen gneiss; orthogneiss; migmatite; ion microprobe; Pb-Pb evaporation; U-Pb; geochronology; zircon; Sweden; Mylonite Zone; Western Segment; Sveconorwegian orogen; Eastern Segment; mineralogy; geochemistry; Petrologi; mineralogi; geokemi;

   Abstract : The Mylonite zone (MZ) is a prominent late-Sveconorwegian lithological terrane boundary in the SW Baltic Shield along which large-scale crustal block movements took place during the Sveconorwegian orogeny. The southern section of the MZ also defines a conspicuous metamorphic break separating upper amphibolite and high-pressure granulite facies rocks in the parautochthonous Eastern Segment (ES), from middle amphibolite facies rocks in the overlying Western Segment (WS). READ MORE

7. 5. Structural chromosomal aberrations and neuropsychiatric disorders

   Author : Tonnie Johannesson; Göteborgs universitet; []
   Keywords : Autism spectrum disorders; chromosomes; FISH; balanced; translocations;

   Abstract : Infantile autism (IA) is a severe neurodevelopment disorder with a complex genetic predisposition. The underlying causes of autism are still not understood. READ MORE